Using digital tools to improve care after acute kidney injury
UPTAKE: Using Personalized Risk and Digital Tools to Guide Transitions Following Acute Kidney Events- A Pragmatic Randomized Controlled Trial in Connect Care
NA · University of Alberta · NCT05806645
This study is testing a new way to improve care for patients recovering from acute kidney injury by creating personalized care plans that help them transition smoothly after leaving the hospital.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 6046 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Alberta (other) |
| Locations | 2 sites (Calgary, Alberta and 1 other locations) |
| Trial ID | NCT05806645 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance post-discharge care for patients who have experienced acute kidney injury (AKI) by co-developing a personalized care plan based on individual risk factors. Utilizing Alberta's new electronic health record system, the study will identify hospitalized patients with AKI and implement a risk-guided transition of care intervention. The approach focuses on addressing gaps in communication, care coordination, and education to improve health outcomes and patient experiences. The study builds on previous pilot work that validated a risk prediction model for AKI survivors.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been hospitalized and diagnosed with acute kidney injury.
Not a fit: Patients with advanced chronic kidney disease, those on dialysis, or with certain other medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the risk of severe health complications following acute kidney injury.
How similar studies have performed: Previous studies have shown promise in using risk-guided strategies for AKI follow-up, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: (all of) * Age ≥ 18 years old * Hospitalized at site using AHS EHR * Acute Kidney Injury (Stage 1-3) identified in hospital per KDIGO guideline criteria Exclusion Criteria: (any of) * Pre-hospitalization advanced CKD: eGFR\<30 mL/min/1.73m2 * Pre-hospitalization dialysis * Very low risk (\<1% risk) of advanced CKD * Non-Alberta resident * Palliative goals of care * Enrolled in the UPTAKE VC Trial * Admitted under a nephrologist at time of discharge * Dialysis on at least 2 days in the last week prior to discharge * Receiving apheresis * Kidney transplant recipient * Diagnosis of Glomerulonephritis * Cirrhosis AND complication of cirrhosis in medical history or active problem list (ascites, varices, hepatic encephalopathy, hepatorenal syndrome)
Where this trial is running
Calgary, Alberta and 1 other locations
- Foothills Medical Centre — Calgary, Alberta, Canada (RECRUITING)
- University of Alberta Hospital — Edmonton, Alberta, Canada (RECRUITING)
Study contacts
- Principal investigator: Neesh Pannu — University of Alberta
- Study coordinator: Neesh Pannu
- Email: npannu@ualberta.ca
- Phone: 780 492 8519
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Kidney Injury