Using diaphragmatic ultrasound to monitor breathing function in ALS patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with Amyotrophic Lateral Sclerosis (ALS) to assess diaphragmatic function using ultrasound techniques. It aims to monitor respiratory impairment, which is a critical aspect of ALS progression, particularly due to phrenic nerve damage leading to diaphragmatic weakness. The study will involve quarterly follow-ups to evaluate diaphragmatic insufficiency in patients who do not yet require non-invasive ventilation. The approach seeks to enhance understanding of respiratory function in ALS and guide timely interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with Amyotrophic Lateral Sclerosis

  * Certain or probable according to the revised Escorial criteria
  * no indication for non-invasive ventilation
* Adult patient
* Patient who has given oral consent
* Patient who speaks and reads French

Exclusion Criteria:

* Patients with pre-existing diaphragmatic dysfunction requiring non-invasive ventilation
* Person who is not affiliated to national health insurance
* Person subject to a legal protection measure (curatorship, guardianship)
* Patients deprived of their liberty
* Pregnant, parturient or breastfeeding women

Where it's running

• Chu Dijon Bourogne
  Dijon, France Recruiting

Study contacts

• Study coordinator: Marjolaine GEORGES
• Email: marjolaine.georges@chu-dijon.fr
• Phone: 03.80.29.37.72

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.