Using diaphragm electrical signals (sEMG) to guide timing of breathing tube removal

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project records surface electromyography (sEMG) from the diaphragm in adult ICU patients who have been mechanically ventilated for over 72 hours and are scheduled for an extubation attempt. Surface electrodes placed on the chest will capture respiratory muscle activity during spontaneous-breathing trials and the extubation process while usual clinical weaning and extubation protocols are followed. Investigators will link sEMG signal patterns to outcomes such as successful extubation versus need for reintubation to identify features associated with readiness. The data collection does not alter routine care but aims to determine whether sEMG could add objective information to current decision-making.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients requiring mechanical ventilation for \>72 hours
* Patients who an attempt at extubation is planned
* Patients who are willing or able to give informed consent (Where consultee advice is sought, informed consent from the participant will be completed as soon as possible).

Exclusion Criteria:

* Aged under 18 years
* Patients admitted with traumatic or spontaneous brain injury
* Patients for who extubation is planned as a palliative process
* Contra-indication to using sEMG e.g., permanent or temporary pacemaker, internal or external cardiac defibrillator, skin lesions around site of electrode placement

Where it's running

• Cardiff and Vale University Health Board
  Cardiff, United Kingdom Recruiting

Study contacts

• Study coordinator: Paul Twose, PhD
• Email: paul.twose@wales.nhs.uk
• Phone: +447739315830

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.