Using Dexmedetomidine to Treat Chronic Knee Pain
Intra-articular Dexmedetomidine for Treatment of Chronic Knee Pain: A Prospective Case-Control Clinical Trial
This study is testing if a new injection using dexmedetomidine can help people with chronic knee pain feel better when other treatments haven't worked.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El Gharbyia) |
| Trial ID | NCT06641206 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of dexmedetomidine, a sedative and analgesic, as a treatment for chronic knee osteoarthritis (KOA) pain. The approach aims to provide an alternative to traditional pain management methods, which often fall short in effectiveness. Patients who are not candidates for surgical intervention will receive intra-articular injections of dexmedetomidine, along with triamcinolone acetonide and bupivacaine hydrochloride, to assess pain relief outcomes. The study seeks to explore the potential of dexmedetomidine in improving the quality of life for those suffering from chronic knee pain.
Who should consider this trial
Good fit: Ideal candidates for this study are patients suffering from chronic knee osteoarthritis who are not candidates for surgical intervention.
Not a fit: Patients who are scheduled for surgical intervention or have uncontrolled medical conditions such as hypertension or diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could offer a new, effective option for managing chronic knee pain in patients who do not qualify for surgery.
How similar studies have performed: While the use of dexmedetomidine in this context is relatively novel, similar studies exploring alternative pain management techniques have shown promise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients were not assigned for surgical intervention; * Patients were free of exclusion criteria Exclusion Criteria: * Patients were assigned for surgical intervention; * Patients who had uncontrolled hypertension and/or diabetes mellitus; * Patients who had uncompensated cardiac, renal, or hepatic diseases; * Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs; * Patients who refused to sign the informed consent were excluded from the study.
Where this trial is running
Tanta, El Gharbyia
- Tanta University — Tanta, El Gharbyia, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.