Using dexmedetomidine to enhance pain relief after kidney surgeries
Effect of Different Doses of Dexmedetomidine Added to Local Anesthetic in Sonographic Guided Erector Spinae Plane Block for Pain Management After Renal Surgeries : Randomized Clinical Trial
This study is testing if adding a medication called dexmedetomidine to a pain relief method can help adults feel less pain after kidney surgery.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut, Assiut Governorate) |
| Trial ID | NCT06899841 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of adding dexmedetomidine to bupivacaine in an Erector Spinae Plane Block for postoperative pain management following renal surgeries. The study aims to evaluate different doses of dexmedetomidine to determine its analgesic effects. Participants will be adults aged 18 to 70 with specific health criteria, and the trial will be conducted at Assiut University Hospitals. The goal is to improve pain control and recovery outcomes for patients undergoing these procedures.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 scheduled for elective renal surgeries with a BMI of 18-35 and ASA physical status I/II.
Not a fit: Patients under 18, those with coagulopathy, or chronic pain syndromes, and individuals refusing the nerve block may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance postoperative pain management for patients undergoing renal surgeries.
How similar studies have performed: Other studies have shown promising results with similar approaches in enhancing postoperative analgesia, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 70 years. * Both sexes, males and females. * Patients with the American Society of Anesthesiologists (ASA) physical status I/II. * Body mass index (BMI) of 18-35 kg/m2 * Patients scheduled for elective Renal or Percutaneous Nephrolithotomy. Exclusion Criteria: * Patients under 18 years. * Patient refusal of nerve block. * Infection at the site of injection. * Coagulopathy. * Allergy to used medications. * Psychiatric disorder or chronic pain syndromes. * Chronic opioid use or substance abuse. * Quadriplegic patients.
Where this trial is running
Asyut, Assiut Governorate
- Assiut University Hospitals — Asyut, Assiut Governorate, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.