Using Dexamethasone to reduce pain after knee surgery
Infiltration Between the Popliteal Artery and Capsule of the Knee Block with Adductor Canal Block with Ropivacaine Vs Ropivacaine and Dexamethasone in Total Knee Arthroplasty: a Randomized Controlled Trial
PHASE4 · Poznan University of Medical Sciences · NCT06470204
This study is testing if adding Dexamethasone to a pain relief method can help older patients feel less pain after knee surgery and reduce their need for opioids.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 65 Years to 100 Years |
| Sex | All |
| Sponsor | Poznan University of Medical Sciences (other) |
| Locations | 1 site (Poznan, Poznań) |
| Trial ID | NCT06470204 on ClinicalTrials.gov |
What this trial studies
This study investigates the effect of adding Dexamethasone to a regional anesthesia technique known as the Infiltration between the Popliteal Artery and Capsule of the Knee Block in patients undergoing Total Knee Arthroplasty. The goal is to assess whether this combination can effectively reduce postoperative pain and inflammation, thereby minimizing the need for opioids and their associated side effects. The study will involve patients aged 65 to 100 who are scheduled for knee surgery and can provide informed consent. Participants will receive either Ropivacaine alone or Ropivacaine combined with Dexamethasone.
Who should consider this trial
Good fit: Ideal candidates are patients aged 65 to 100 scheduled for total knee arthroplasty who can provide informed consent.
Not a fit: Patients with cognitive impairments or language barriers that prevent them from providing informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and opioid consumption for patients undergoing knee surgery.
How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled for total hip arthroplasty * patients aged \>65 and \<100 years * patients able to provide informed consent * patients able to reliably report symptoms to the research team Exclusion Criteria: * inability to provide first-party consent due to cognitive impairment or a language barrier
Where this trial is running
Poznan, Poznań
- Poznan University of Medical Sciences — Poznan, Poznań, Poland (RECRUITING)
Study contacts
- Study coordinator: Malgorzata Domagalska, M.D. Ph.D.
- Email: mdomagalska@ump.edu.pl
- Phone: (61) 873-83-03
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis