Using dexamethasone in adductor canal blocks for knee surgery pain management
Perineural Dexamethasone in the Adductor Canal Block for Postoperative Pain in Knee Arthroplasty Surgery
This study is testing if adding dexamethasone to a pain relief injection can help people having knee surgery feel less pain for longer without affecting their ability to move.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Sex | All |
| Sponsor | University Tunis El Manar Academic / other |
| Locations | 1 site (Tunis, La Mannouba) |
| Trial ID | NCT06079047 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of adding perineural dexamethasone to the adductor canal block for managing postoperative pain in patients undergoing total knee arthroplasty (TKA). Patients will be randomly assigned to receive either a combination of bupivacaine and dexamethasone or a control solution. The study aims to determine if dexamethasone can prolong the duration of sensory block, thereby improving pain management without compromising mobility. Pre-anesthesia evaluations will ensure patient safety and consent prior to the procedure.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for unilateral total knee arthroplasty under spinal anesthesia with ASA class I, II, or III.
Not a fit: Patients with contraindications to regional anesthesia, those undergoing bilateral TKA, or those with poorly controlled diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance postoperative pain control for TKA patients, facilitating quicker recovery and rehabilitation.
How similar studies have performed: Previous studies have shown promising results with the use of dexamethasone in regional anesthesia, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for unilateral TKA * Surgery under spinal anesthesia * ASA class I, II, and III patients Exclusion Criteria: * Patient refusal to participate in the study * Contraindication to regional anesthesia * Allergies to the products used * Bilateral TKA * Revision TKA * TKA in the context of inflammatory or post-traumatic disease * BMI \> 45 * Poorly controlled diabetic patients with HbA1c \> 8% * Patients on corticosteroid therapy or who have received an intra-articular injection of corticosteroids
Where this trial is running
Tunis, La Mannouba
- Kaabachi — Tunis, La Mannouba, Tunisia (Recruiting)
Study contacts
- Study coordinator: Olfa Kaabachi, Md
- Email: olfa.kaabachi@gnet.tn
- Phone: 216 98317381
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.