Using deep rTMS to treat neuropathic pain and fibromyalgia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the efficacy and safety of deep repetitive transcranial magnetic stimulation (rTMS) using an H-coil for patients suffering from neuropathic pain or fibromyalgia. It is a randomized, double-blind, sham-controlled trial lasting three months, where participants will receive either active or sham rTMS sessions. The treatment involves five daily sessions followed by weekly sessions, with a total of up to ten weeks of treatment. The primary outcome measure is the percentage of pain relief assessed at week 13.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Chronic pain ≥ 6 months, at least 4/10 on a 0-10 NRS, present every day or nearly every day
* Neuropathic pain (confirmed with Douleur Neuropathique en 4 questions and international criteria from NeuPSIG) or fibromyalgia (revised ACR criteria)
* Stable concomitant medications for pain for at least one month
* Able to fill out questionnaires and understand and speak French

Exclusion Criteria:

* Contraindications to rTMS
* Prior treatment with rTMS
* Progressive severe condition (eg cancer)
* Psychosis
* Psychoactive drug abuse

Where it's running

• Inserm U987
  Boulogne-Billancourt, France Recruiting
• Centre d'Evaluation et de Traitement de la douleur
  Paris, France Not yet recruiting

Study contacts

• Study coordinator: Nadine ATTAL
• Email: nadine.attal@aphp.fr
• Phone: 0033149095931

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.