Using deep learning to assess liver diseases with ultrasound data
Official title: Acquisition and Frequency Spectroscopic Evaluation of Broadband Clinical Ultrasound Raw Data for Liver Cirrhosis and Focal Pathologies Using Neural Networks for Tissue and Pathology Differentiation
Run by Technische Universität Dresden · NCT06317181 · Data updated 2026-11-12
This study is testing if a new deep learning method using ultrasound data can better identify liver diseases in patients compared to traditional methods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Technische Universität Dresden Academic / other |
| Locations | 4 sites (Dresden and 3 other locations) |
| Status | Recruiting |
| Started | April 1, 2024 |
| Main results expected | October 2025 |
| Study ends | December 2025 |
| Registry record updated | August 20, 2025 |
| Trial ID | NCT06317181 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients scheduled for an ultrasound investigation due to suspected liver disease.
✕Probably not a fit
Patients who have undergone recent liver interventions or contrast-enhanced ultrasounds may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of neural networks trained on raw ultrasound radiofrequency data for assessing liver diseases in patients undergoing ultrasound examinations. The study will compare the performance of these neural networks against traditional elastography methods and other neural networks trained on standard b-mode images. Participants will undergo clinical elastography and additional ultrasound assessments to establish a reliable ground truth for the evaluation. The goal is to determine if the deep learning approach can accurately identify diffuse liver diseases and distinguish focal liver pathologies from healthy tissue.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate and efficient assessments of liver diseases, improving patient outcomes.
How similar studies have gone: While the use of deep learning in medical imaging is gaining traction, this specific application of neural networks on ultrasound radiofrequency data is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * scheduled for an ultrasound investigation by an independent physician * signed declaration of consent Exclusion Criteria: * smaller interventions in the same liver during the last 2 Week (for example liver biopsy) * contrast enhanced ultrasound less than a day ago * major intervention at the liver (for example partial resection)
Where it's running
-
University Hospital
Dresden, Germany Recruiting -
Diakonissen Hospital Dresden
Dresden, Germany Recruiting -
University Hospital Halle (Saale)
Halle, Germany Recruiting -
University Hospital Leipzig
Leipzig, Germany Recruiting
Study contacts
- Principal investigator: Moritz Herzog, MD — University Hospital Dresden
- Study coordinator: Moritz Herzog, MD
- Email: moritz.herzog@ukdd.de
- Phone: 0049 351 458 11501
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.