Clinical trial Recruiting at 4 sites Interventional Ages 18 and up

Using deep learning to assess liver diseases with ultrasound data

Official title: Acquisition and Frequency Spectroscopic Evaluation of Broadband Clinical Ultrasound Raw Data for Liver Cirrhosis and Focal Pathologies Using Neural Networks for Tissue and Pathology Differentiation

Run by Technische Universität Dresden · NCT06317181 · Data updated 2026-11-12

This study is testing if a new deep learning method using ultrasound data can better identify liver diseases in patients compared to traditional methods.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorTechnische Universität Dresden
Academic / other
Locations4 sites (Dresden and 3 other locations)
StatusRecruiting
StartedApril 1, 2024
Main results expectedOctober 2025
Study endsDecember 2025
Registry record updatedAugust 20, 2025
Trial IDNCT06317181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for an ultrasound investigation due to suspected liver disease.

Probably not a fit

Patients who have undergone recent liver interventions or contrast-enhanced ultrasounds may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of neural networks trained on raw ultrasound radiofrequency data for assessing liver diseases in patients undergoing ultrasound examinations. The study will compare the performance of these neural networks against traditional elastography methods and other neural networks trained on standard b-mode images. Participants will undergo clinical elastography and additional ultrasound assessments to establish a reliable ground truth for the evaluation. The goal is to determine if the deep learning approach can accurately identify diffuse liver diseases and distinguish focal liver pathologies from healthy tissue.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate and efficient assessments of liver diseases, improving patient outcomes.

How similar studies have gone: While the use of deep learning in medical imaging is gaining traction, this specific application of neural networks on ultrasound radiofrequency data is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* scheduled for an ultrasound investigation by an independent physician
* signed declaration of consent

Exclusion Criteria:

* smaller interventions in the same liver during the last 2 Week (for example liver biopsy)
* contrast enhanced ultrasound less than a day ago
* major intervention at the liver (for example partial resection)

Where it's running

  • University Hospital
    Dresden, Germany
    Recruiting
  • Diakonissen Hospital Dresden
    Dresden, Germany
    Recruiting
  • University Hospital Halle (Saale)
    Halle, Germany
    Recruiting
  • University Hospital Leipzig
    Leipzig, Germany
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.