Using CPAP devices to help recover cochlear receptor cells in patients with obstructive sleep apnea
The Role of the Device Operating Under the Continuous Positive Airway Pressure in the Recovery Process of Cochlear Receptor Cells in Patients With Obstructive Sleep Apnea
This study is testing if using CPAP devices can help people with obstructive sleep apnea recover damaged hearing cells in their ears.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 45 (estimated) |
| Ages | 25 Years to 79 Years |
| Sex | All |
| Sponsor | Osijek University Hospital Academic / other |
| Locations | 1 site (Osijek) |
| Trial ID | NCT05362890 on ClinicalTrials.gov |
What this trial studies
This study investigates the potential damage to cochlear receptor cells in patients with obstructive sleep apnea syndrome (OSAS) due to recurrent hypoxia. It aims to determine the extent of this damage based on the severity of the condition and to explore whether the use of continuous positive airway pressure (CPAP) devices can facilitate recovery of these cells. Participants will be divided into a target group with OSAS and a control group of healthy individuals, with assessments conducted through questionnaires and polysomnography. The study is being conducted at the University Hospital Center Osijek.
Who should consider this trial
Good fit: Ideal candidates include adults diagnosed with moderate to severe obstructive sleep apnea who have undergone prior evaluation for sleep disorders.
Not a fit: Patients under 18 years old or those with previous neurootological diseases requiring surgical treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved hearing outcomes for patients with obstructive sleep apnea by promoting the recovery of cochlear receptor cells.
How similar studies have performed: While the approach of using CPAP devices for cochlear recovery is innovative, similar studies have shown varying degrees of success in related areas of sleep apnea treatment.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with OSAS who have been previously examined by a neurologist for sleep disorders, have undergone polysomnography, and have been diagnosed with moderate or severe obstructive sleep apnea according to the AHI index * Healthy individuals for control group that will consist of subjects in whom specific questionnaires excluded the existence of obstructive sleep apnea. Exclusion Criteria: * age less than 18 years, * persons with previous neurootological diseases that required surgical treatment * persons who deviate from the research protocol.
Where this trial is running
Osijek
- Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Osijek — Osijek, Croatia (Recruiting)
Study contacts
- Study coordinator: Mirjana Grebenar Čerkez
- Email: mirjanagrebenar@gmail.com
- Phone: +38598682429
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.