Using CoQ10 to reduce inflammation and organ dysfunction in heart surgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the protective effects of Coenzyme Q10 (CoQ10) supplementation in adults undergoing cardiovascular surgery. It aims to determine whether CoQ10 can mitigate inflammatory responses and organ dysfunction associated with such procedures, independent of other lifestyle changes. Participants will receive CoQ10 alongside standard medical therapy to assess its efficacy in improving surgical outcomes. The study focuses on patients with decreased CoQ10 levels and mitochondrial dysfunction, which are common in cardiovascular disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult men and women
* Who receive cardiovascular surgery
* Agree to participate in the surgery and sign the informed consent form

Exclusion Criteria:

* Pregnant or planning on getting pregnant during the study
* Contain a minimum of 2 traits of metabolic syndrome
* Refused to participate in the surgery and refused informed consent

Where it's running

• Beijing Anzhen Hospital
  Beijing, Beijing Municipality, China Recruiting
• The First Affiliated Hospital of Guangzhou Medical University
  Guangzhou, Guangdong, China Recruiting
• The First Affiliated Hospital of Nanjing Medical University
  Nanjing, Jiangsu, China Recruiting
• West China Hospital of Sichuan University
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Hong Liu, MD
• Email: dr.hongliu@foxmail.com
• Phone: 8618801281613

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.