Using cold saline to reduce pain after root canal treatment
Effectiveness of Intracanal Cryotherapy on Post Operative Pain After Root Canal Therapy in Patients with Symptomatic Apical Periodontitis
This study tests if using cold saline during root canal treatment can help reduce pain for people with tooth infections.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | All |
| Sponsor | Armed Forces Institute of Dentistry, Pakistan Academic / other |
| Locations | 1 site (Rawalpindi, Punjab Province) |
| Trial ID | NCT06785753 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of intracanal cryotherapy using cold saline to alleviate post-operative pain in patients undergoing root canal treatment for symptomatic apical periodontitis. Participants will be randomly assigned to either a control group receiving room temperature saline or a cold group receiving saline at 2.5°C during the final irrigation phase of the procedure. Pain levels will be assessed using a visual analogue scale before and after treatment. The study aims to determine if the temperature of the irrigation solution can significantly impact pain management in dental procedures.
Who should consider this trial
Good fit: Ideal candidates include systemically healthy patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis who report a pre-treatment pain score of less than 8.
Not a fit: Patients who are on preoperative analgesics or antibiotics, have calcified canals, or are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management strategies for patients undergoing root canal treatments.
How similar studies have performed: While there is limited data on the specific use of cryotherapy in this context, similar studies exploring temperature effects on pain management have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis * maxillary or mandibular single rooted teeth * systemically healthy patients * patients having pain score \< 8 Exclusion Criteria: * patients on preoperative analgesics or antibiotics within past 12 hours * teeth with calcified canals and previously treated teeth * tooth with immature apices or resorption * patients allergic to local anesthesia * pregnant or lactating mothers * patients who are immunocompromised .
Where this trial is running
Rawalpindi, Punjab Province
- Armed Forces Institute of Dentistry — Rawalpindi, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Hira Amjad, BDS — Armed Forces Institude Of Dentistry
- Study coordinator: Hira Amjad, BDS
- Email: anmolamjad03@gmail.com
- Phone: 03345294071
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.