Using cognitive behavioral therapy to help parents of premature infants in the NICU

Parental Perception of Child Vulnerability in the NICU and Development Outcomes: A Randomized Control Trial Preventative Intervention With Cognitive Behavioral Therapy

Not applicable Interventional University of Texas Southwestern Medical Center · NCT03906435

This study is testing whether cognitive behavioral therapy can help parents of premature infants in the NICU feel less anxious and depressed, which may improve their relationship with their child and the child's development.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
SexAll
SponsorUniversity of Texas Southwestern Medical Center Academic / other
Locations1 site (Dallas, Texas)
Trial IDNCT03906435 on ClinicalTrials.gov

What this trial studies

This study aims to improve outcomes for both parents and their premature infants who have spent time in the neonatal intensive care unit (NICU) through cognitive behavioral therapy (CBT) sessions for parents. The NICU experience can lead to significant stress and mental health issues for parents, which may alter their perceptions of their child's vulnerability and impact parenting styles. By addressing these mental health challenges, the study seeks to mitigate the effects of Vulnerable Child Syndrome (VCS) and enhance developmental outcomes for infants. The research will evaluate the effectiveness of CBT in reducing parental anxiety, depression, and PTSD, and its subsequent impact on parent-child relationships.

Who should consider this trial

Good fit: Ideal candidates for this study are parents of infants born at Parkland Hospital who are English or Spanish speaking and whose infants were born at or before 30.6 weeks gestation.

Not a fit: Patients with significant congenital anomalies or those involved with Child Protective Services may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved mental health for parents and better developmental outcomes for their premature infants.

How similar studies have performed: Previous studies have shown that cognitive behavioral therapy can effectively reduce anxiety and depression in NICU parents, suggesting potential success for this approach in addressing VCS.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Born at Parkland Hospital
* English or Spanish speaking mother +/- father
* ≤ 30.6 weeks gestation at birth
* Survival to 33 weeks gestation

Exclusion Criteria:

* Significant congenital anomalies
* Child Protective Services (CPS) involvement or foster care placement -- Prior enrollment in this PreVNT study for an older sibling.

Where this trial is running

Dallas, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Premature InfantMental Health IssueDevelopment, ChildParent-Child RelationsVulnerable Child SyndromeNeonatal Intensive Care UnitCognitive Behavioral TherapyParental Perception of Child Vulnerability
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.