Using Coenzyme Q10 to Reduce Pain After Lung Surgery
Official title: The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery: a Randomized Controlled Trial
Run by The Second Affiliated Hospital of Chongqing Medical University · NCT06743802 · Data updated 2026-11-12
This study is testing if Coenzyme Q10 can help reduce pain after lung surgery for adults aged 18-75.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 264 (estimated) |
| Sponsor | The Second Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Status | Recruiting |
| Started | January 9, 2025 |
| Main results expected | March 20, 2026 |
| Study ends | March 20, 2026 |
| Registry record updated | February 26, 2025 |
| Trial ID | NCT06743802 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-75 scheduled for elective lung resection surgery who are in good health according to ASA classifications I-III.
✕Probably not a fit
Patients with a history of chronic pain or those who have previously undergone thoracoscopic surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of Coenzyme Q10 in preventing both acute and chronic postoperative pain in patients undergoing thoracoscopic lung resection surgery. Participants will be randomly assigned to receive either Coenzyme Q10 or a placebo, with the aim of assessing pain levels post-surgery. The study focuses on the potential benefits of Coenzyme Q10 in reducing the incidence and severity of pain, thereby improving recovery outcomes for patients. The trial is designed for individuals aged 18-75 who meet specific health criteria and are scheduled for elective surgery.
Why it matters
Potential benefit: If successful, this study could significantly reduce postoperative pain and improve recovery for patients undergoing thoracoscopic surgery.
How similar studies have gone: While the use of Coenzyme Q10 for pain management is not widely tested, similar studies on its effects in other contexts have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-75 years; * American Society of Anesthesiology (ASA) physical status classification I-III; * Scheduled for elective lung resection surgery under thoracoscopy; * Voluntarily opting for patient-controlled intravenous analgesia; * Willing to participate in this trial after consultation with the patient or their family and signing the informed consent form. Exclusion Criteria: * History of previous thoracotomy or thoracoscopic surgery; * Patients converted to open thoracotomy intraoperatively; * Severe hepatic or renal dysfunction; * History of substance abuse; * Pregnancy or breastfeeding; * History of chronic pain; * Use of coenzyme Q10 for more than one month; * Allergy to coenzyme Q10; * Patients unable to communicate or cooperate.
Where it's running
-
Guangyou Duan
Chongqing, Chongqing Municipality, China Recruiting
Study contacts
- Study coordinator: Guangyou Duan, ph.D
- Email: duangy@hospital.cqmu.edu.cn
- Phone: (+86)18323376014
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.