Using cetylated fatty acid to reduce pain after knee surgery
Efficacy of Cetylated Fatty Acid for Alleviating Postoperative Pain After Total Knee Arthroplasty: A Randomized Placebo-controlled Trial
NA · Thammasat University · NCT06300008
This study is testing if a special cream made from cetylated fatty acid can help reduce pain after knee surgery for people aged 50 to 80 who have had a total knee replacement due to arthritis.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Sponsor | Thammasat University (other) |
| Locations | 1 site (Khlong Luang, Pathumthani) |
| Trial ID | NCT06300008 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of cetylated fatty acid against a placebo in alleviating postoperative pain following unilateral total knee arthroplasty (TKA). The hypothesis is that applying cetylated fatty acid topically can help reduce pain and inflammation after the surgery. Participants will be aged between 50 and 80 years and must have undergone TKA due to osteoarthritis. The study will involve monitoring pain levels and inflammation post-surgery to assess the efficacy of the treatment.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50-80 who have osteoarthritis and are scheduled for unilateral primary TKA.
Not a fit: Patients with inflammatory knee arthritis, previous knee surgeries, or skin issues around the knee may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce postoperative pain and improve recovery for patients undergoing knee surgery.
How similar studies have performed: While there is limited information on the specific use of cetylated fatty acid for this purpose, similar approaches targeting postoperative pain management have shown promise in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 50-80 years * Osteoarthritic knee patients underwent unilateral primary TKA * Participants understand and consent to the protocol of the trial Exclusion Criteria: * Inflammatory knee arthritis * Previous knee surgery or trauma * Previous knee infection * Skin problem around the knee such as eczema, psoriasis, wound infection * Allergy to studied drug
Where this trial is running
Khlong Luang, Pathumthani
- department of orthopaedic surgery, Faculty of medicine, Thammasat university — Khlong Luang, Pathumthani, Thailand (RECRUITING)
Study contacts
- Principal investigator: Supakit Kanitnate, MD — Thammasat University Hospital
- Study coordinator: Supakit Kanitnate, M.D.
- Email: naypeng@hotmail.com
- Phone: 66899853635
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Pain, Postoperative Inflammation, Cetylated fatty acid, TKA, Postoperative pain, Inflammation