Using cardiac MRI to detect heart issues in sarcoidosis patients
Detection and Prognostic Significance of Myocardial Damage Visualized by Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
This study is testing if a special heart scan can help find hidden heart problems in people with sarcoidosis that might be affecting their health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 27000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Duke University Academic / other |
| Locations | 1 site (Durham, North Carolina) |
| Trial ID | NCT01745237 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of cardiac magnetic resonance (CMR) imaging in identifying cardiac involvement in patients diagnosed with sarcoidosis. By comparing CMR results with standard clinical evaluations, the study seeks to uncover unrecognized cardiac damage that may contribute to mortality in these patients. Participants will include those with biopsy-proven sarcoidosis and suspected cardiac involvement, who will undergo CMR in addition to routine assessments.
Who should consider this trial
Good fit: Ideal candidates are individuals with biopsy-proven sarcoidosis and suspected cardiac involvement.
Not a fit: Patients with contraindications to MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection and better management of cardiac complications in sarcoidosis patients.
How similar studies have performed: Other studies have shown promise in using CMR for detecting cardiac involvement in sarcoidosis, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Biopsy proven sarcoidosis * Suspected cardiac sarcoidosis Exclusion Criteria: * Contraindication to MRI
Where this trial is running
Durham, North Carolina
- Duke University Medical Center — Durham, North Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Raymond J Kim, MD — Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center
- Study coordinator: Han W Kim, MD
- Email: kim00050@duke.edu
- Phone: 919-668-3539
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.