Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using cardiac MRI to detect heart issues in sarcoidosis patients

Official title: Prognostic Value of Clinical Cardiovascular MRI

Run by Duke University · NCT01745237 · Data updated 2026-11-12

This study is testing if a special heart scan can help find hidden heart problems in people with sarcoidosis that might be affecting their health.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment27000 (estimated)
SponsorDuke University
Academic / other
Locations1 site (Durham, North Carolina)
StatusRecruiting
StartedSeptember 2002
Main results expectedJune 2032
Study endsJune 2032
Registry record updatedOctober 16, 2026
Trial IDNCT01745237 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals with biopsy-proven sarcoidosis and suspected cardiac involvement.

Probably not a fit

Patients with contraindications to MRI will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of cardiac magnetic resonance (CMR) imaging in identifying cardiac involvement in patients diagnosed with sarcoidosis. By comparing CMR results with standard clinical evaluations, the study seeks to uncover unrecognized cardiac damage that may contribute to mortality in these patients. Participants will include those with biopsy-proven sarcoidosis and suspected cardiac involvement, who will undergo CMR in addition to routine assessments.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection and better management of cardiac complications in sarcoidosis patients.

How similar studies have gone: Other studies have shown promise in using CMR for detecting cardiac involvement in sarcoidosis, indicating a potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Scheduled to undergo routine clinical CMR scan

Exclusion Criteria:

* Contraindication to MRI

Where it's running

  • Duke University Medical Center
    Durham, North Carolina, United States
    Recruiting

Study contacts

  • Principal investigator: Raymond J Kim, MD — Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center
  • Study coordinator: Han W Kim, MD
  • Email: kim00050@duke.edu
  • Phone: 919-668-3539

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Two prednisolone tapering plans for people with stable sarcoidosis

    The team will try two different prednisolone tapering plans to see if people with stable sarcoidosis taking 5–10 mg/day can safely cut their dose by at least half.

    Recruiting Royal Brompton & Harefield NHS Foundation Trust · London · NCT07498842

  • Immune cells in lung disease and how they could guide immunotherapy

    This project sees if immune cell profiling from blood can explain why people with lung cancer, sarcoidosis, or COPD respond differently to immunotherapy or develop chronic lung inflammation.

    Recruiting Université Catholique de Louvain · Brussels · NCT07384897

  • Imaging in Inflammatory Heart Diseases linked to autoimmune disorders

    This study tests how well multimodality imaging (CMR, echocardiography, and PET) detects inflammation in people with suspected inflammatory heart or autoimmune rheumatic diseases.

    Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07077304

  • Virtual groups to reduce sarcoidosis-related fatigue

    This project tests whether an 8-week virtual Mindfulness-Based Stress Reduction (MBSR) program can help reduce fatigue and improve anxiety and depression in adults with sarcoidosis compared with a monthly virtual support group.

    Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07073963

  • Counting and classifying inflammatory cells in uveitis with OCT

    This project will try to use high-resolution OCT scans to count and categorize inflammatory cells and proteins in people with anterior uveitis and related eye inflammation.

    Recruiting Oregon Health and Science University · Portland, Oregon · NCT07065747

  • Comparing yoga and physiotherapy for sarcoidosis treatment

    This study is testing whether yoga or traditional physiotherapy helps people with sarcoidosis improve their lung function and feel better overall.

    Recruiting Saglik Bilimleri Universitesi · Istanbul, Maltepe · NCT06848608

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.