Using cardiac MRI to assess risk in patients with dilated cardiomyopathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with dilated cardiomyopathy (DCM), a condition characterized by reduced left ventricular function and dilation. It aims to utilize cardiac magnetic resonance imaging (CMR) to evaluate cardiac mass, volume, and function, which can aid in risk stratification and differential diagnosis. The study will include patients with a left ventricular ejection fraction of less than 50% and significant dilation, while excluding those with ischemic heart disease or other specific cardiac conditions. The findings could provide valuable insights into the prognosis and management of DCM.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. reduced left ventricular ejection fraction (LVEF\<50%)
2. LV end-diastolic volume \>2SD from normal according to normograms corrected by body surface area (BSA) and age.

Exclusion Criteria:

1. Any evidence indicating the presence of ischemic heart disease:

   Coronary angiography, perfusion imaging Medical documentation that indicated the presence of ischemic heart disease An infarct pattern of late gadolinium enhancement on cardiac magnetic resonance studies and/or acute coronary syndrome or coronary revascularization during follow-up
2. Any evidence of hypertrophic cardiomyopathy, or moderate-to-severe valvular disease\[18\], or infiltrative disease (such as amyloidosis, sarcoidosis, Fabry disease)
3. Incessant arrhythmias
4. Inability to lie flat
5. Pregnancy
6. Contraindication to cardiac magnetic resonance including severe claustrophobia, defibrillators, pacemakers, certain types of intracranial aneurysm clips, intraocular metal, and Stage IV/V chronic kidney disease
7. Diabetes mellitus with end organ damage
8. Inability to provide informed consent.

Where it's running

• Fuwai Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Minjie Lu, PhD
• Email: coolkan@163.com
• Phone: +86-10-88396941

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.