Using bupivacaine nebulization to reduce pain after lung surgery
Pain Managment After VATS to Reduce Postoperative Pain and Improve Pulmonary Function
This study is testing if using a special breathing treatment with bupivacaine can help reduce pain after lung surgery for patients undergoing video-assisted thoracic surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut, Assuit) |
| Trial ID | NCT05282251 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of intrapleural nebulization of bupivacaine to alleviate postoperative pain in patients undergoing video-assisted thoracic surgery (VATS). The approach aims to provide better distribution of the local anesthetic while minimizing the amount needed, thus reducing potential side effects associated with higher doses. Patients will receive bupivacaine nebulization along with intravenous paracetamol and ketorolac for pain management. The study focuses on patients classified as ASA class 1-3 who are scheduled for VATS under general anesthesia.
Who should consider this trial
Good fit: Ideal candidates for this study are patients classified as ASA class 1-3 scheduled for video-assisted thoracic surgery.
Not a fit: Patients with allergies to local anesthetics, recent pneumonia, or significant renal or hepatic dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery outcomes for patients undergoing lung surgery.
How similar studies have performed: While the use of local anesthetics in various forms has been explored, the specific approach of nebulization for postoperative pain management in VATS is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients that reach American socity of anesthesiologist class 1-3 * Scheduled for VATS surgery under general anesthesia. Exclusion Criteria: * ● Allergy to local anesthetics * Patient with pleural inflammation due to recent pneumonia * Patients who are unable or unwilling to perform spirometer test * Renal dysfunction: (Elevated creatinine \> 2 mg\\dl) * Hepatic dysfunction: (Elevated hepatic enzymes three times above normal value) * History of addiction
Where this trial is running
Asyut, Assuit
- Assiut University — Asyut, Assuit, Egypt (Recruiting)
Study contacts
- Study coordinator: Esam Moubarak Sahin
- Email: Emobarak94@gmail.com
- Phone: 01094878158
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.