Using brain stimulation to improve movement and reduce fatigue in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of multi-session anodal transcranial direct current stimulation (tDCS) on the left dorsolateral prefrontal cortex in patients with Parkinson's disease. The researchers aim to determine if this noninvasive brain stimulation technique can enhance motor function and decrease motor fatigue and fatigability. Participants will receive tDCS for 20 minutes daily over five days, with assessments conducted to evaluate changes in their motor abilities and fatigue levels. The study seeks to provide insights into the long-term benefits of tDCS for improving quality of life in individuals with Parkinson's disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of PD with at least two of the four diagnostic criteria for PD (tremor, rigidity, bradykinesia, and postural instability)
* Must be able to consent

Exclusion Criteria:

* Patients with dementia (MOCA \< 21)
* PD treatment using deep brain stimulation (DBS)
* Diagnosis of psychosis
* Diagnosis of multiple sclerosis
* Diagnosis of stroke
* Diagnosis of chronic obstructive pulmonary disease (COPD)
* Diagnosis of congestive heart failure (CHF)

Where it's running

• Sanford Brain and Spine Center
  Fargo, North Dakota, United States Recruiting

Study contacts

• Principal investigator: Jau-Shin Lou, MD — Sanford Health
• Study coordinator: Jessica Keller, B.S.
• Email: jessica.keller@sanfordhealth.org
• Phone: 701-417-5781

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.