Using brain stimulation to improve breathing in COPD patients

The Effect of Transcranial Direct Current Stimulation (tDCS) on Dyspnoea Perception, Pulmonary Function and Functional Level During COPD Exacerbation

NA · Okan University · NCT06944626

This study is testing whether a type of brain stimulation can help people with COPD breathe better and feel more comfortable during flare-ups.

Quick facts

PhaseNA
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorOkan University (other)
Locations1 site (İstanbul, Zeytinburnu)
Trial IDNCT06944626 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of transcranial direct current stimulation (tDCS) on patients with chronic obstructive pulmonary disease (COPD) experiencing exacerbations. It aims to assess how tDCS can influence dyspnea perception, pulmonary function, and overall functional levels during these episodes. The study compares the effects of tDCS with sham stimulation and conventional physiotherapy to determine the most effective approach for improving respiratory function and quality of life. Participants will be closely monitored to evaluate changes in their symptoms and physical capabilities.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old diagnosed with COPD who are currently hospitalized due to an exacerbation.

Not a fit: Patients with significant comorbidities, recent surgeries, or those on invasive mechanical ventilation may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the quality of life for COPD patients by reducing dyspnea and improving lung function.

How similar studies have performed: While tDCS is a novel approach in this context, similar studies have shown promise in modulating brain activity for pain relief and rehabilitation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with COPD and followed up for at least 6 months
* Hospitalised due to an exacerbation
* Have not taken any medication affecting the nervous system in the last 6 months
* Co-operative
* Have the ability to participate in working procedures
* Over 18 years of age,
* The specialist physician finds it suitable for physiotherapy applications,
* Volunteers who want to participate in the study

Exclusion Criteria:

* Having comorbidities other than COPD, such as bronchiectasis, lung cancer or asthma
* Surgery in the last 6 months (volume reduction surgery, etc.)
* Neuromuscular disease
* Pulmonary embolism or pulmonary oedema
* Presence of cranial, cardiac, spinal cord, intra-aural metal implants
* Epilepsy
* Patients on invasive mechanical ventilation
* Patient with cardiac pace maker

Where this trial is running

İstanbul, Zeytinburnu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: COPD, Dyspnea, tDCS, fNIRS, Pulmonary function

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.