Using Brachial Plexus Block for Patients with Cerebral Aneurysms Treated via Transradial Access
Effect of Brachial Plexus Block on Outcomes of Upper Extremity Arteries After Intracranial Aneurysm Interventional Surgery Via Transradial Access: A Randomized Clinical Trial
This study is testing whether a special nerve block can help patients with brain aneurysms treated through their wrist have better outcomes and fewer complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 176 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital with Nanjing Medical University Academic / other |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT06035692 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a brachial plexus block (BPB) on the outcomes of upper extremity arteries in patients undergoing embolization of intracranial aneurysms through a transradial approach. It is a multicenter, prospective clinical trial where participants are randomly assigned to receive either BPB or a control treatment. The primary outcomes include the incidence of radial artery spasm and the condition of the radial artery for future interventions, assessed through angiography and ultrasound. Secondary outcomes involve evaluating intraoperative complications and surgeon satisfaction.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-75 with a BMI under 28, scheduled for elective interventional surgery for intracranial aneurysms via transradial access.
Not a fit: Patients with allergies to local anesthetics, existing vascular issues, or those who refuse to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could reduce complications related to radial artery spasm and improve outcomes for patients undergoing cerebral aneurysm procedures.
How similar studies have performed: While the specific application of BPB in this context may be novel, similar studies have shown promising results in reducing complications in vascular interventions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-75 years old, BMI\<28kg/m2 * ASA physical status Ⅰ-Ⅲ * Elective interventional surgery for intracranial aneurysms via TRA * willing to sign informed consent Exclusion Criteria: * patients allergic to local anesthetics * neck infection on the surgical side * Preoperative upper extremity ultrasound or DSA showed radial artery occlusion and arteriovenous fistula * The diameter of radial artery was still less than 2mm after brachial plexus block * Axillary artery occlusion and other vascular anatomical abnormalities may affect the operation * Radial artery patency: Barbeau type D * The history of hand trauma may affect the establishment of radial artery; access, or the use of radial artery as a bypass or dialysis vessel * patients with incomplete block effect after nerve block were detected; * The patient refused to participate in the study or cooperate with the follow-up
Where this trial is running
Nanjing, Jiangsu
- The First Affiliated Hospital with Nanjing Medical University — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Principal investigator: Jingjin Li, M.D — The First Affiliated Hospital with Nanjing Medical University
- Study coordinator: Feng Feng, M.D
- Email: 316637881@qq.com
- Phone: 13814073686
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.