Using binaural sound to enhance anesthesia induction with remimazolam

The Effect of Preoperative Binaural Sound on Remimazolam Dose Required for Induction of General Anesthesia: a Randomized, Placebo-controlled Trial

NA · Gangnam Severance Hospital · NCT06099977

This study tests if listening to binaural sound can help patients fall asleep faster when getting anesthesia with remimazolam.

Quick facts

PhaseNA
Study typeInterventional
Enrollment72 (estimated)
Ages20 Years and up
SexAll
SponsorGangnam Severance Hospital (other)
Locations1 site (Seoul)
Trial IDNCT06099977 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of binaural sound in reducing the time it takes for patients to lose consciousness during general anesthesia induction with remimazolam. The study involves administering binaural sound alongside a remimazolam infusion to assess its impact on anesthesia induction times. Participants will be monitored for their response to the sound and medication combination. The goal is to determine if this approach can improve the efficiency of anesthesia induction.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20-60 scheduled for general anesthesia with a physical status classification of 1-2 and an ideal body weight of 50-80 kg.

Not a fit: Patients with hearing disabilities, recent opioid or sedative use, or certain medical conditions such as cardiovascular disease or liver failure may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to faster and more efficient anesthesia induction for patients undergoing surgery.

How similar studies have performed: While the use of binaural sound in anesthesia is a novel approach, similar studies exploring sound therapy in medical settings have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients scheduled for generla anesthesia
2. Patients aged 20-60
3. Patients with American Society of Anesthesiologist physical status classification 1-2
4. Patients with ideal body weight 50-80 kg

Exclusion Criteria:

1. Patients with hearing disability
2. Patients using opioids or sedatives in 1 week
3. Patients who are dependent for alcoholics or drugs
4. Patients with hypersensitivities to remimazolam
5. Patients with arrhythmia, cardiovascular disease, heart failure, or hypovolemia
6. Patients with liver failure

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: General Anesthesia, Prostate Cancer, Uterine Myoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.