Using baclofen to treat anxiety and alcohol use disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of baclofen in treating alcohol use disorder (AUD) among patients, particularly focusing on those with varying levels of anxiety symptoms. Participants who are already on baclofen will complete questionnaires over a six-week period to assess their drinking behaviors, anxiety levels, and other related factors. The study aims to determine if higher anxiety symptoms correlate with fewer abstinent days and other treatment outcomes. By analyzing these responses, the trial seeks to provide insights into the relationship between anxiety and alcohol use in patients receiving baclofen.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meeting DSM-5 criteria for AUD
* Able to understand and provide written consent
* Already receiving baclofen or started with baclofen at start of hospitalization
* Therapeutic desire towards alcohol abstinence

Exclusion Criteria:

* Concurrent substance use disorder other than nicotine or cannabis
* Clinically significant psychiatric illness that requires pharmacotherapy, unless stable and no changes in medication has been made in the last 30 days
* Clinically significant medical diseases that may pose a risk to continuing baclofen use
* Pregnant or currently breastfeeding women

Where it's running

• Universitair Ziekenhuis Brussel
  Jette, Brussels Capital, Belgium Recruiting

Study contacts

• Principal investigator: Cleo L Crunelle — Universitair Ziekenhuis Brussel
• Study coordinator: Cleo L Crunelle
• Email: cleo.crunelle@vub.be
• Phone: +32 477 77 22

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.