Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using B-OK Bottles to boost HIV and ART literacy in South Africa

Official title: Evaluating the Impact of Using the B-OK Bottles for HIV and ART Literacy in South Africa

Run by University of Pennsylvania · NCT07703891 · Data updated 2026-11-12

This study tests whether low-cost B-OK bottles help adults in Gauteng understand HIV, ART, and U=U better, compared with standard information or a short video.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorUniversity of Pennsylvania
Academic / other
Locations1 site (Johannesburg, Gauteng)
StatusRecruiting
StartedJuly 27, 2026
Main results expectedFebruary 2027
Study endsMarch 2027
Registry record updatedNovember 6, 2026
Trial IDNCT07703891 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) residing in Gauteng, able to consent, and willing to attend a follow-up visit.

Probably not a fit

Participants who do not benefit from visualization-based education or who have barriers to applying the information may see little personal change.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial evaluates three approaches to patient education about HIV treatment in Gauteng, South Africa. Participants are adults living with HIV who will be assigned to: standard-of-care information, in-person B-OK bottle education, or a video-based B-OK bottle education. The study aims to see which method most effectively increases knowledge and may influence adherence and attitudes toward U=U. Outcomes focus on understanding of ART and the concept that undetectable viral load means untransmittable HIV. The investigation is conducted with collaboration between the University of Pennsylvania, HE2RO, and the University of the Witwatersrand, at the HE2RO offices in Johannesburg.

Why it matters

Potential benefit: If successful, the tool could improve ART understanding and adherence, potentially leading to better viral suppression.

How similar studies have gone: Previous work suggests visual educational tools can enhance health knowledge, but the effectiveness of B-OK bottles in HIV care is novel in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 18 years or older
* Residing in Gauteng
* Able to understand and communicate in English or another study-supported language
* Willing to attend an in-person study visit at the HE2RO offices
* Willing to provide contact details for follow-up at six weeks

Exclusion Criteria:

* Unwilling or unable to provide written informed consent for study participation

Where it's running

  • Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand
    Johannesburg, Gauteng, South Africa
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.