Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using arterial embolization to treat bone metastases

Official title: Embolizzazione Arteriosa Per il Trattamento Delle Metastasi Ossee: Studio Osservazionale Prospettico

Run by Istituto Ortopedico Rizzoli · NCT06189079 · Data updated 2026-11-12

This study is testing whether a minimally invasive treatment called arterial embolization can help reduce pain and improve outcomes for patients with bone metastases.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorIstituto Ortopedico Rizzoli
Academic / other
Locations1 site (Bologna, Emilia-Romagna)
StatusRecruiting
StartedMay 10, 2023
Main results expectedAugust 2027
Study endsAugust 2028
Registry record updatedMay 12, 2026
Trial IDNCT06189079 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with single or oligometastatic bone lesions who have a life expectancy of more than three months.

Probably not a fit

Patients with severe functional status impairment, life expectancy of less than three months, or specific contraindications such as hypovascular metastasis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the use of arterial embolization as a minimally invasive treatment for patients with bone metastases. It aims to evaluate the effectiveness of this method in reducing pain, controlling local disease, and minimizing peri-operative bleeding. The study will include patients who are candidates for embolization therapy and will monitor their outcomes over time. The approach is designed to provide insights into the benefits and risks associated with this treatment modality.

Why it matters

Potential benefit: If successful, this treatment could significantly improve pain management and quality of life for patients with bone metastases.

How similar studies have gone: Previous studies have shown promising results with arterial embolization for similar conditions, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of either sex of age or older who are candidates for embolization therapy
* Life expectancy \> 3 months
* Single metastatic or oligometastatic.
* Plurimetastatic if a particular site is causing painful symptoms or at risk for pathologic rupture

Exclusion Criteria:

* Patients with life expectancy \<3 months or severe functional status impairment (ASA 4)
* Patients with hypovascular metastasis documented by angiography or MRI perfusion study with MDC.
* Patients with coagulation deficiency or plateletopenic patients.
* Patients with documented active infection.

Where it's running

  • Istituto Ortopedico Rizzoli
    Bologna, Emilia-Romagna, Italy
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.