Using antioxidant-rich media to improve embryo quality in IVF

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effect of antioxidant-enriched culture media on the euploidy rates of embryos during in vitro fertilization (IVF). It aims to address the negative impact of reactive oxidative species (ROS) on embryo development by utilizing a culture medium that contains higher concentrations of antioxidants. The trial will involve a randomized approach using sibling oocytes from patients undergoing assisted reproductive technology cycles. The primary goal is to determine if this improved culture condition can enhance the quality of embryos suitable for implantation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing assisted reproductive technology cycles when ICSI is indicated.
* Patients when Iin vitto fertilization (IVF) is also performed will be included as far as there are enough oocytes for ICSI randomization. However, IVF oocytes will not be used for the study.
* Maternal age 18-43 years old.
* PGT-A cycles with only trophectoderm biopsies on day 5/6/7.
* Patients with more than 6 COCs expected for ICSI.
* Body mass index \<35.
* Fresh and frozen ejaculated sperm.

Exclusion Criteria:

* PGT-M cycles
* Fresh and frozen testicular sperm.

Where it's running

• ART Fertility Clinics LLC
  Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates Recruiting

Study contacts

• Study coordinator: Daniela Nogueira
• Email: daniela.nogueira@artfertilityclinics.com
• Phone: +971504374961

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.