Using antimicrobial catheters to prevent infections in ICU patients in Malaysia
Efficacy & Health Economics of Antimicrobial-impregnated Central Venous Catheters (CVCs) Compared to Non-impregnated CVCs in Central Line-associated Bloodstream Infection Prevention in a Malaysia University Hospital Adult ICU
This study is testing whether special catheters that fight germs can help prevent infections in critically ill patients in the ICU at Universiti of Malaya Medical Centre.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 110 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | University of Malaya Academic / other |
| Locations | 1 site (Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur) |
| Trial ID | NCT05959018 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the efficacy and cost-effectiveness of antimicrobial-impregnated central venous catheters (CVCs) in preventing central line-associated bloodstream infections (CLABSIs) among critically ill patients in the ICU at Universiti of Malaya Medical Centre. The study will compare the outcomes of patients using these specialized catheters against those using standard non-impregnated catheters. By assessing both the clinical outcomes and the economic implications, the trial seeks to provide a comprehensive understanding of the benefits of antimicrobial catheters in critical care settings. This research is particularly significant as it addresses a gap in local studies regarding the effectiveness and cost of these devices.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are admitted to the ICU and require a central venous catheter during their stay.
Not a fit: Patients with pre-existing infections or those who refuse to participate in the study will not benefit from this trial.
Why it matters
Potential benefit: If successful, this study could lead to reduced infection rates and healthcare costs for critically ill patients requiring central venous access.
How similar studies have performed: Previous studies have shown promising results regarding the efficacy of antimicrobial-impregnated CVCs, but this specific evaluation in a Malaysian context is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years old and above who are admitted to the ICU of UMMC during the study period * Patients who require a CVC during ICU stay Exclusion Criteria: * Patients who refuse to participate in the study * Patients with known hypersensitivity reaction to CVC materials * Patients with pre-existing diagnosis of CLABSI upon admission to the ICU * Patients with pre-existing bloodstream infection upon admission to the ICU * Patients with a pre-existing CVC, where sterility during placement may be compromised (e.g. in an emergency situation) * Patients with indwelling CVC less than 48 hours * Patients who had poor compliance to catheter bundle care during CVC handling throughout the indwelling catheter period * Patients who require \> 1 CVC or other central venous access
Where this trial is running
Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
- Universiti of Malaya Medical Centre — Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia (Recruiting)
Study contacts
- Principal investigator: Kai Ming Tan — University of Malaya
- Study coordinator: Kai Ming Tan
- Email: kaiming.pg91@gmail.com
- Phone: +60174787668
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.