Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using ANI to improve pain management after jaw surgery

Official title: Comparison of Goal-directed Analgesia Using ANI (Analgesia/Nociception Index) and Standard Analgesia During General Anesthesia in Patients Undergoing Orthognathic Surgery on Postoperative Quality of Recovery: a Prospective Randomized Controlled Trial

Run by Seoul National University Hospital · NCT06205355 · Data updated 2026-11-12

This study tests if using a special pain monitoring tool can help people recover better and manage pain after jaw surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment86 (estimated)
SponsorSeoul National University Hospital
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedJanuary 25, 2024
Main results expectedDecember 25, 2026
Study endsDecember 30, 2026
Registry record updatedJanuary 16, 2024
Trial IDNCT06205355 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients aged 18 or older who are scheduled for maxillary, mandibular, or bimaxillary surgery under general anesthesia.

Probably not a fit

Patients with severe comorbidities, emergency surgery needs, or chronic pain conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of goal-directed analgesia using the Analgesia/Nociception Index (ANI) to enhance postoperative recovery in patients undergoing maxillofacial surgery. By monitoring pain levels through ANI, the study aims to tailor analgesic interventions to individual patient needs. The approach focuses on improving pain management and overall recovery outcomes following surgical procedures involving the maxilla and mandible.

Why it matters

Potential benefit: If successful, this approach could lead to better pain control and faster recovery for patients undergoing jaw surgery.

How similar studies have gone: While the use of ANI in pain management is gaining interest, this specific application in maxillofacial surgery is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients 18 or older undergoing maxillary, mandibular, or bimaxillary surgery under general anesthesia.
* adult patients who can provide written informed consent to participate in the study, understand the procedures of this study, and be able to complete patient-reported questionnaires adequately.
* adult patients who Have made an informed decision to participate in this study and have given written consent.

Exclusion Criteria:

* Patients with ASA physical status 4-5
* Emergency surgery
* Patients with chronic pain and related pain medications
* Patients with hypersensitivity to general anesthesia drugs and pain medications
* Patients with arrhythmia
* Pregnant women
* Others deemed unsuitable by the investigator

Where it's running

  • Seoul National University Children's Hospital
    Seoul, South Korea
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.