Using ANI to improve pain management after jaw surgery
Official title: Comparison of Goal-directed Analgesia Using ANI (Analgesia/Nociception Index) and Standard Analgesia During General Anesthesia in Patients Undergoing Orthognathic Surgery on Postoperative Quality of Recovery: a Prospective Randomized Controlled Trial
Run by Seoul National University Hospital · NCT06205355 · Data updated 2026-11-12
This study tests if using a special pain monitoring tool can help people recover better and manage pain after jaw surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 86 (estimated) |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | January 25, 2024 |
| Main results expected | December 25, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | January 16, 2024 |
| Trial ID | NCT06205355 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients aged 18 or older who are scheduled for maxillary, mandibular, or bimaxillary surgery under general anesthesia.
✕Probably not a fit
Patients with severe comorbidities, emergency surgery needs, or chronic pain conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of goal-directed analgesia using the Analgesia/Nociception Index (ANI) to enhance postoperative recovery in patients undergoing maxillofacial surgery. By monitoring pain levels through ANI, the study aims to tailor analgesic interventions to individual patient needs. The approach focuses on improving pain management and overall recovery outcomes following surgical procedures involving the maxilla and mandible.
Why it matters
Potential benefit: If successful, this approach could lead to better pain control and faster recovery for patients undergoing jaw surgery.
How similar studies have gone: While the use of ANI in pain management is gaining interest, this specific application in maxillofacial surgery is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients 18 or older undergoing maxillary, mandibular, or bimaxillary surgery under general anesthesia. * adult patients who can provide written informed consent to participate in the study, understand the procedures of this study, and be able to complete patient-reported questionnaires adequately. * adult patients who Have made an informed decision to participate in this study and have given written consent. Exclusion Criteria: * Patients with ASA physical status 4-5 * Emergency surgery * Patients with chronic pain and related pain medications * Patients with hypersensitivity to general anesthesia drugs and pain medications * Patients with arrhythmia * Pregnant women * Others deemed unsuitable by the investigator
Where it's running
-
Seoul National University Children's Hospital
Seoul, South Korea Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.