Using an iPhone app to help adolescents and young adults lose weight after stem cell transplant

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients (BWL001)

Not applicable Interventional Jonsson Comprehensive Cancer Center · NCT04453072

This study is testing whether an iPhone app and coaching can help young people lose weight after they've had a stem cell transplant.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages13 Years to 30 Years
SexAll
SponsorJonsson Comprehensive Cancer Center Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT04453072 on ClinicalTrials.gov

What this trial studies

This trial evaluates the effectiveness of a smartphone application combined with telephone coaching to promote weight loss in adolescents and young adults who are overweight or obese following hematopoietic stem cell transplantation. Participants will receive an iPhone with the W8Loss2Go app, a body scale, and a digital food scale to track their weight and food intake daily. They will interact with coaches through text messages and weekly phone calls for support and progress discussions, along with telemedicine interviews to address barriers to weight management. The study aims to assess not only weight outcomes but also changes in metabolic parameters, physical activity, and adherence to the intervention.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults who are at least 100 days post-hematopoietic stem cell transplantation and classified as obese.

Not a fit: Patients who are less than 100 days post-transplant or do not meet the obesity criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could help adolescents and young adults achieve significant weight loss and develop healthier eating habits post-transplant.

How similar studies have performed: Other studies have shown promise in using technology-based interventions for weight management, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study
* Patients must classify as obese, represented as body mass index (BMI) \>= 85th percentile for age and gender
* Patients must also be able to read English since the app intervention is only available in English form
* No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation
* PARENT:
* His/her child meets all inclusion criteria
* \>= 18 years of age
* Can speak English

Exclusion Criteria:

* Patients who are \< 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are \> 100 days post-transplant at their next consultation that falls within the enrollment window
* Patients whose BMI does not fall under the obese category will be excluded

Where this trial is running

Los Angeles, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ObesityMalignant Neoplasm
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.