Using an iPhone app to help adolescents and young adults lose weight after stem cell transplant
Official title: Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients (BWL001)
Run by Jonsson Comprehensive Cancer Center · NCT04453072 · Data updated 2026-11-12
This study is testing whether an iPhone app and coaching can help young people lose weight after they've had a stem cell transplant.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 13 Years to 30 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Jonsson Comprehensive Cancer Center Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Status | Recruiting |
| Started | July 1, 2020 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT04453072 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents and young adults who are at least 100 days post-hematopoietic stem cell transplantation and classified as obese.
✕Probably not a fit
Patients who are less than 100 days post-transplant or do not meet the obesity criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of a smartphone application combined with telephone coaching to promote weight loss in adolescents and young adults who are overweight or obese following hematopoietic stem cell transplantation. Participants will receive an iPhone with the W8Loss2Go app, a body scale, and a digital food scale to track their weight and food intake daily. They will interact with coaches through text messages and weekly phone calls for support and progress discussions, along with telemedicine interviews to address barriers to weight management. The study aims to assess not only weight outcomes but also changes in metabolic parameters, physical activity, and adherence to the intervention.
Why it matters
Potential benefit: If successful, this intervention could help adolescents and young adults achieve significant weight loss and develop healthier eating habits post-transplant.
How similar studies have gone: Other studies have shown promise in using technology-based interventions for weight management, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study * Patients must classify as obese, represented as body mass index (BMI) \>= 85th percentile for age and gender * Patients must also be able to read English since the app intervention is only available in English form * No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation * PARENT: * His/her child meets all inclusion criteria * \>= 18 years of age * Can speak English Exclusion Criteria: * Patients who are \< 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are \> 100 days post-transplant at their next consultation that falls within the enrollment window * Patients whose BMI does not fall under the obese category will be excluded
Where it's running
-
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States Recruiting
Study contacts
- Principal investigator: Theodore B Moore — UCLA / Jonsson Comprehensive Cancer Center
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.