Using AI to recommend treatments for gastrointestinal cancers
Application of Large Language Models in the Recommendation of Treatment Plans for Gastrointestinal Cancers
This study is testing if using AI, like ChatGPT, can help suggest better treatment plans for people with gastrointestinal cancers compared to traditional recommendations from doctors.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chinese Academy of Sciences Government |
| Locations | 7 sites (Duarte, California and 6 other locations) |
| Trial ID | NCT06002425 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of ChatGPT in suggesting treatment plans for patients with gastrointestinal cancers by analyzing both retrospective and prospective data. Medical records from over 1,200 patients will be collected, with a portion used to explore various prompt methods for treatment recommendations. A multidisciplinary team will assess the AI's suggestions against those of clinicians. Additionally, 400 participants will be randomly assigned to receive either clinician-only recommendations or ChatGPT-assisted plans, allowing for a comparison of treatment outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a confirmed diagnosis of gastric or colorectal cancer and complete medical records available.
Not a fit: Patients with cancers other than gastrointestinal cancers or those receiving treatment across multiple hospitals may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance treatment decision-making for patients with gastrointestinal cancers, potentially leading to improved outcomes.
How similar studies have performed: While the use of AI in treatment recommendations is a growing field, this specific application of ChatGPT for gastrointestinal cancers is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years, both male and female. * Pathologically confirmed diagnosis of gastrointestinal cancer (gastric cancer or colorectal Cancer). * Detailed medical records available prior to treatment (including chief complaint, history of present illness, radiological examinations, pathological examinations, laboratory tests, etc.). * Participants will receive complete treatment in the participating hospitals. Exclusion Criteria: * Participants with cancers other than gastrointestinal cancers. * Participants who receive treatment in multiple hospitals.
Where this trial is running
Duarte, California and 6 other locations
- City of Hope — Duarte, California, United States (Not_yet_recruiting)
- Jiangmen Central Hospital — Jiangmen, Guangdong, China (Recruiting)
- The Fifth Affiliated Hospital of Sun Yat-sen University — Zhuhai, Guangdong, China (Recruiting)
- Zhuhai People's Hospital — Zhuhai, Guangdong, China (Recruiting)
- Peking University Cancer Hospital (Inner Mongolia Campus) — Hohhot, Inner Mongolia, China (Recruiting)
- University Hospital Magdeburg — Magdeburg, Saxony-Anhalt, Germany (Not_yet_recruiting)
- San Raffaele University Hospital, Italy — Milan, Italy (Not_yet_recruiting)
Study contacts
- Principal investigator: Di Dong, PhD — Institute of Automation, Chinese Academy of Sciences
- Study coordinator: Di Dong, PhD
- Email: di.dong@ia.ac.cn
- Phone: +86 13811833760
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.