Clinical trial Recruiting at 4 sites Interventional Ages 18 and up

Using AI to recommend treatments for gastrointestinal cancers

Official title: Application of Large Language Models in the Recommendation of Treatment Plans for Gastrointestinal Cancers

Run by Chinese Academy of Sciences · NCT06002425 · Data updated 2026-11-12

This study is testing if using AI, like ChatGPT, can help suggest better treatment plans for people with gastrointestinal cancers compared to traditional recommendations from doctors.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorChinese Academy of Sciences
Government
Locations7 sites (Duarte, California and 6 other locations)
StatusRecruiting
StartedAugust 29, 2023
Main results expectedSeptember 30, 2023
Study endsDecember 31, 2028
Registry record updatedSeptember 8, 2023
Trial IDNCT06002425 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a confirmed diagnosis of gastric or colorectal cancer and complete medical records available.

Probably not a fit

Patients with cancers other than gastrointestinal cancers or those receiving treatment across multiple hospitals may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of ChatGPT in suggesting treatment plans for patients with gastrointestinal cancers by analyzing both retrospective and prospective data. Medical records from over 1,200 patients will be collected, with a portion used to explore various prompt methods for treatment recommendations. A multidisciplinary team will assess the AI's suggestions against those of clinicians. Additionally, 400 participants will be randomly assigned to receive either clinician-only recommendations or ChatGPT-assisted plans, allowing for a comparison of treatment outcomes.

Why it matters

Potential benefit: If successful, this approach could enhance treatment decision-making for patients with gastrointestinal cancers, potentially leading to improved outcomes.

How similar studies have gone: While the use of AI in treatment recommendations is a growing field, this specific application of ChatGPT for gastrointestinal cancers is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years, both male and female.
* Pathologically confirmed diagnosis of gastrointestinal cancer (gastric cancer or colorectal Cancer).
* Detailed medical records available prior to treatment (including chief complaint, history of present illness, radiological examinations, pathological examinations, laboratory tests, etc.).
* Participants will receive complete treatment in the participating hospitals.

Exclusion Criteria:

* Participants with cancers other than gastrointestinal cancers.
* Participants who receive treatment in multiple hospitals.

Where it's running

  • Jiangmen Central Hospital
    Jiangmen, Guangdong, China
    Recruiting
  • The Fifth Affiliated Hospital of Sun Yat-sen University
    Zhuhai, Guangdong, China
    Recruiting
  • Zhuhai People's Hospital
    Zhuhai, Guangdong, China
    Recruiting
  • Peking University Cancer Hospital (Inner Mongolia Campus)
    Hohhot, Inner Mongolia, China
    Recruiting
  • City of Hope
    Duarte, California, United States
    Not yet recruiting
  • University Hospital Magdeburg
    Magdeburg, Saxony-Anhalt, Germany
    Not yet recruiting
Show 1 more location
  • San Raffaele University Hospital, Italy
    Milan, Italy
    Not yet recruiting

Study contacts

  • Principal investigator: Di Dong, PhD — Institute of Automation, Chinese Academy of Sciences
  • Study coordinator: Di Dong, PhD
  • Email: di.dong@ia.ac.cn
  • Phone: +86 13811833760

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.