Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Using AI to Improve Rehabilitation for Patients with Severe Mental Disorders

Official title: Prediction and Intervention Effect of Rehabilitation Status for Severe Mental Disorder Patients Based on Multimodal Analysis and AI Agents

Run by Shanghai Mental Health Center · NCT06904079 · Data updated 2026-11-12

This study is testing if using AI and fun games can help people with severe mental disorders improve their social skills and get back into the community.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment82 (estimated)
SponsorShanghai Mental Health Center
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedMarch 12, 2024
Main results expectedJune 30, 2026
Study endsJune 30, 2026
Registry record updatedAugust 17, 2025
Trial IDNCT06904079 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 to 65 diagnosed with severe mental disorders such as schizophrenia or bipolar disorder, who are registered in the Shanghai Mental Health Information Management System.

Probably not a fit

Patients with severe physical illnesses or organic brain diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study integrates multimodal technology, reinforcement learning, and agent-based modeling to enhance the rehabilitation of patients with severe mental disorders. It involves three phases: first, assessing user needs through community mental health facilities; second, designing and implementing gamified interventions followed by a randomized controlled trial; and third, optimizing these interventions based on user feedback and data analysis. The goal is to improve social functions and facilitate reintegration into society for these patients.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the quality of life and social integration for patients with severe mental disorders.

How similar studies have gone: While the integration of AI and gamification in mental health rehabilitation is a novel approach, similar studies have shown promise in enhancing patient engagement and outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Registered in the Shanghai Mental Health Information Management System,

  * Diagnosed patients with one of the six severe mental disorders: schizophrenia, schizoaffective disorder, paranoid psychosis, bipolar (affective) disorder, mental disorder due to epilepsy, and mental retardation accompanied by mental disorder,

    * Aged between 18 and 65 years old, ④ Normal vision or hearing, or within the normal range after correction, ⑤ Patients or their families have provided informed consent for this study and signed the informed consent form.

Exclusion criteria:

Patients with severe physical illnesses or organic brain diseases.

Where it's running

  • Shanghai Mental Health Center
    Shanghai, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.