Using AI to improve lens power calculations for cataract surgery
The 1000 Eyes Lens Power Trial: Introducing Artificial Intelligence to Intraocular Lens Power Calculation
This study is testing a new AI method to see if it can make lens power calculations for cataract surgery more accurate for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 21 Years to 110 Years |
| Sex | All |
| Sponsor | Johannes Kepler University of Linz Academic / other |
| Locations | 1 site (Linz, Upperaustria) |
| Trial ID | NCT05779319 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop an artificial intelligence approach to enhance the accuracy of intraocular lens power calculations for cataract surgery. By analyzing data from 1000 patients who have undergone cataract surgery, the study will compare the new AI method against conventional calculation formulas and assess refractive errors based on different eye lengths. Additionally, it will utilize a ray tracing method to identify sources of error in patients experiencing significant refractive surprises. The study will be conducted across multiple centers, focusing on patients with specific eligibility criteria.
Who should consider this trial
Good fit: Ideal candidates include pseudophakic patients aged 21 years and older who have undergone uncomplicated cataract surgery within the last 4 weeks to 24 months.
Not a fit: Patients with multifocal intraocular lenses or those who have undergone combined surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate lens power calculations, reducing postoperative refractive errors and improving patient outcomes after cataract surgery.
How similar studies have performed: While some studies have explored AI in lens power calculations, this approach is relatively novel and aims to provide a more advanced solution compared to existing methods.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pseudophakic (at least one eye): cataract surgery between 4 weeks and 24 months prior to recruitment * If both eyes would be suitable for the study only the right eye will be included, if only one eye is suitable for the study, this eye will be included * Pre-operative swept-source OCT biometry available (no ultrasound measurement for axial eye length) * Uncomplicated cataract surgery * Age 21 years and older Exclusion Criteria: * Multifocal IOLs * Combined surgery (cataract plus glaucoma/vitreoretinal/corneal surgery) * Best corrected distance visual acuity below 0.5 Snellen * In case of pregnancy (pregnancy test will be taken preoperatively in women of reproductive age)
Where this trial is running
Linz, Upperaustria
- Kepler University Klinik Departement of Opthalmology — Linz, Upperaustria, Austria (Recruiting)
Study contacts
- Principal investigator: Nino Hirnschall, MD — JKU Linz
- Study coordinator: Nino Hirnschall, MD
- Email: nino.hirnschall@kepleruniklinikum.at
- Phone: +435768083
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.