Using AI to diagnose Helicobacter Pylori infection and gastric lesions
Official title: Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion: A Randomized Clinical Trial
Run by National Taiwan University Hospital · NCT05762991 · Data updated 2026-11-12
This study is testing whether artificial intelligence can help doctors in rural areas diagnose Helicobacter pylori infections and early signs of stomach cancer by looking at images from endoscopies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 80 Years |
| Sex | All |
| Enrollment | 6000 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | December 24, 2021 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT05762991 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 20-80 who are scheduled for a urea breath test and endoscopy.
✕Probably not a fit
Patients with a history of gastric surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the effectiveness of artificial intelligence in diagnosing Helicobacter pylori infection and premalignant gastric lesions through the analysis of upper endoscopic images. Patients will undergo a urea breath test, upper gastrointestinal endoscopy, and histological examination, with their results and images collected for analysis. The study seeks to establish a telemedicine system that assists clinicians in rural areas with diagnosis based on these images, linking baseline predictions to potential future gastric cancer cases.
Why it matters
Potential benefit: If successful, this approach could enhance diagnostic accuracy and accessibility for patients in rural areas suffering from gastric conditions.
How similar studies have gone: Other studies have shown promise in using artificial intelligence for diagnostic purposes, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 20-80 2. Scheduled endoscopy Exclusion Criteria: 1\. History of gastric surgery
Where it's running
-
Yi-Chia Lee
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Tsung-Hsien Chiang, MD, PhD — National Taiwan University Hospital
- Study coordinator: Yi-Chia Lee, MD, PhD
- Email: yichialee@ntu.edu.tw
- Phone: 886-2-23123456
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Fecal transplant to help eradicate stubborn Helicobacter pylori infection
This study tests whether giving a fecal microbiota transplant can help people with Helicobacter pylori infection that has not responded to standard treatments.
-
Fecal-guided simplified vonoprazan plus clarithromycin first-line therapy for H. pylori
We are testing whether a two-drug regimen of vonoprazan plus clarithromycin clears H. pylori in adults whose fecal PCR shows no clarithromycin resistance mutations.
-
Bismuth-amoxicillin-vonoprazan triple therapy versus bismuth-based quadruple therapy for H. pylori infection
This will test whether a 14-day bismuth-amoxicillin-vonoprazan triple therapy works better and is as safe as a 14-day bismuth-based quadruple therapy for adults with H. pylori infection.
-
P-CABs plus bismuth quadruple treatment for Helicobacter pylori infection
This study tests whether using potassium-competitive acid blockers (P-CABs) in bismuth-containing quadruple therapy works better and is safe for adults with H. pylori infection.
-
Bismuth versus no bismuth for treating H. pylori-related stomach and duodenal ulcers in children
This project will try adding bismuth to standard antibiotic and PPI treatment to see if it helps clear H. pylori and heal ulcers in children.
-
Tegoprazan 50 mg twice daily plus amoxicillin versus vonoprazan 20 mg twice daily plus amoxicillin for H. pylori eradication
This trial tests whether a 14-day tegoprazan plus amoxicillin regimen works as well as a vonoprazan plus amoxicillin regimen to cure Helicobacter pylori infection in adults.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.