Using AI to analyze facial expressions in healthy individuals and those with cognitive decline or dementia

Preliminary Study Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia

Observational National Taiwan University Hospital · NCT06513403

This study is testing whether AI can help spot differences in facial expressions between healthy people and those with cognitive decline or dementia to improve early detection of these conditions.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages50 Years to 75 Years
SexAll
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Hsinchu)
Trial IDNCT06513403 on ClinicalTrials.gov

What this trial studies

This observational study employs artificial intelligence technology to examine and identify differences in facial expressions among three groups: healthy individuals, patients experiencing cognitive decline, and those diagnosed with dementia. By analyzing these facial expressions, the research aims to develop a novel screening tool for dementia, potentially aiding in early detection and intervention strategies. The study focuses on participants aged 50 to 75, with specific cognitive assessment criteria to categorize them into experimental and control groups. The findings could contribute to promoting healthy aging and reducing the burden of dementia on families and healthcare systems.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 50 to 75, including those with mild cognitive impairment, moderate dementia, and healthy controls.

Not a fit: Patients outside the age range of 50 to 75 or those unable to follow instructions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection of dementia, allowing for timely interventions that enhance patient outcomes.

How similar studies have performed: While the use of AI in analyzing facial expressions is a novel approach, similar studies have shown promise in enhancing dementia screening methods.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age between 50 and 75 years.

* Experimental group:
* MCI group: CDR score of 0.5 or MMSE score between 20-25 (mild/early stage).
* Dementia group: CDR score greater than 1 or MMSE score between 10-19 (moderate/middle stage).
* Control group:
* Health group: MMSE score of 26 or above.
* Participants must be conscious and able to follow instructions.

Where this trial is running

Hsinchu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Artificial Intelligence TechnologyCognitive DeclineDementiaIdentifyFacial Expressionsartificial intelligence technologycognitive declinedementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.