Using advanced ultrasound to track blood flow in healthy and injured tendons
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Tendinopathic Tendons
University Hospital Bispebjerg and Frederiksberg · NCT06142747
This study is testing a new ultrasound method to see if it can help spot differences in blood flow in healthy and injured tendons, specifically for people with overuse injuries like Achilles and patellar tendinopathy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 135 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University Hospital Bispebjerg and Frederiksberg (other) |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT06142747 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate a novel ultrasound technique called Super Resolution ultrasound imaging of Erythrocytes (SURE) to visualize and quantify the microvasculature in tendons affected by overuse injuries, specifically the Achilles and patellar tendons. Participants will undergo a non-invasive ultrasound examination to assess blood flow characteristics and vessel structure, comparing those with tendinopathy to healthy individuals. The study seeks to determine if SURE can detect subtle differences in blood vessel characteristics that may aid in diagnosing and treating tendon injuries.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 to 70 with a BMI below 30 who can lie still for the ultrasound examination.
Not a fit: Patients with conditions such as diabetes, arthritis, or those who have had recent injuries to the tendon may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for tendon injuries, enhancing treatment strategies and patient outcomes.
How similar studies have performed: While Doppler ultrasound has been commonly used, this study explores a novel approach with SURE, which has not been extensively tested in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 to 70 years of age. * BMI below 30. * Able to lie still for 1 minute. * Capable of providing signed informed consent. Exclusion Criteria: * Pregnancy. * Dementia. * Smoking. * Diabetes. * Arthritis. * Current or historical injuries to the tendon or surrounding tissue aside from tendinopathy. * Medical or surgical treatments for their tendinopathy that may influence blood flow.
Where this trial is running
Copenhagen
- Institute of Sports Medicine — Copenhagen, Denmark (RECRUITING)
Study contacts
- Study coordinator: Rene B Svensson, PhD
- Email: rene.brueggebusch.svensson@regionh.dk
- Phone: +45 38635870
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Tendinopathy, Tendon Overuse Injury, Achilles Tendon, Patellar Tendon, Ultrasonography