Using advanced MRI techniques to evaluate diabetic kidney disease
the Value of Multimodal Magnetic Resonance Imaging in the Diagnosis and Treatment Monitoring of Diabetic Kidney Disease
Shengjing Hospital · NCT06452862
This study is testing whether advanced MRI scans can help doctors better diagnose and track kidney problems in people with diabetes without needing invasive tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Shengjing Hospital (other) |
| Locations | 1 site (Shenyang, Liaoning) |
| Trial ID | NCT06452862 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of multimodal magnetic resonance imaging (MRI) in diagnosing and monitoring diabetic kidney disease (DKD). It aims to establish a non-invasive method for assessing DKD progression by combining imaging techniques with biochemical indicators. Diabetic patients at various stages of DKD will undergo regular MRI examinations to explore the relationship between imaging findings and kidney function changes. The goal is to improve the accuracy of DKD diagnosis and treatment monitoring without the need for invasive procedures.
Who should consider this trial
Good fit: Ideal candidates for this study are diabetic patients without other diseases affecting renal function.
Not a fit: Patients with renal function damage from non-diabetic causes or those with significant organ dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate and non-invasive diagnosis and monitoring of diabetic kidney disease.
How similar studies have performed: While multimodal MRI techniques have shown promise in other areas, this specific application in diabetic kidney disease is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically diagnosed diabetic kidney disease (DKD) * Age 18-80 years Exclusion Criteria: * Malignant tumor, active infection, or life expectancy \<1 year * Pregnancy or lactation * MRE contraindications (metal implants, claustrophobia, severe arrhythmia) or poor image quality * eGFR \<15 mL/min/1.73m² or receiving renal replacement therapy * Other primary kidney diseases or systemic diseases affecting renal function
Where this trial is running
Shenyang, Liaoning
- Shengjing Hospital — Shenyang, Liaoning, China (RECRUITING)
Study contacts
- Principal investigator: Yu Shi, M.D. — Shengjing Hospital
- Study coordinator: Yu Shi, M.D.
- Email: 18940259980@163.com
- Phone: 18940259980
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Diabetic Kidney Disease, Magnetic Resonance Imaging, Magnetic Resonance Elastography, Diabetes