Using advanced imaging to improve recovery after eye surgery
Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies: Biomarkers of Morpho-Functional Recovery by Artificial Intelligence
This study is testing if advanced imaging can help doctors predict how well patients will recover after eye surgery for issues like macular holes and retinal detachment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Months and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Rome) |
| Trial ID | NCT05747144 on ClinicalTrials.gov |
What this trial studies
This study aims to identify morphological and functional biomarkers that can predict post-operative recovery in patients undergoing vitreoretinal surgery for conditions such as macular holes and retinal detachment. By utilizing machine learning techniques and decisional support systems, the research seeks to analyze multimodal big data to enhance patient assessment and personalize surgical approaches. The goal is to better target patients who are likely to benefit from surgery, thereby improving outcomes and recovery times.
Who should consider this trial
Good fit: Ideal candidates include adults scheduled for vitreoretinal surgery due to macular holes, epiretinal membranes, retinal detachment, or macular dystrophies.
Not a fit: Patients under 18 years of age or those unable to undergo morphological examinations due to poor cooperation or media opacity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients undergoing vitreoretinal surgery.
How similar studies have performed: Other studies utilizing machine learning and multimodal imaging in ophthalmology have shown promising results, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients to undergo vitreo-retinal surgery for: 1. Macular hole 2. Epiretinal membranes 3. Retinal detachment 4. Macular dystrophies (retinal pre-prosthesis) Exclusion Criteria: * Patients under 18 years of age will be excluded; patients in whom morphological examinations cannot be performed due to poor cooperation or opacity of the dioptric media (e.g. corneal pathology). Quality of morphological images inadequate for post acquisition processing (\<6/10).
Where this trial is running
Rome
- Prof. Stanislao Rizzo — Rome, Italy (Recruiting)
Study contacts
- Study coordinator: Maria Cristina Savastano, MD,PhD
- Email: mariacristina.savastano@unicatt.it
- Phone: +39 3384443002
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.