Using advanced imaging to improve lens surgery outcomes
Official title: Study on the Application of Intraoperative Optical Coherence Tomography Technique in the Diagnosis and Treatment of Lens Diseases
Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT06687356 · Data updated 2026-11-12
This study is testing whether a special imaging technique can help doctors plan better and reduce problems during lens surgery for patients with eye issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Second Affiliated Hospital, Zhejiang University, School of Medicine Academic / other |
| Locations | 2 sites (Hangzhou, Zhejiang and 1 other locations) |
| Status | Recruiting |
| Started | November 27, 2024 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | May 22, 2025 |
| Trial ID | NCT06687356 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with lens opacity or abnormal positioning requiring surgical intervention.
✕Probably not a fit
Patients with other serious eye diseases affecting visual prognosis or significant systemic diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the use of intraoperative optical coherence tomography (OCT) to enhance the diagnosis and treatment of lens diseases during surgery. It focuses on analyzing the relationship between preoperative and intraoperative changes in the anterior segment of the eye and the resulting surgical outcomes. By accurately assessing these changes, the study aims to improve surgical planning and reduce complications. The ultimate goal is to enhance the quality of care for patients undergoing lens surgery.
Why it matters
Potential benefit: If successful, this approach could lead to better surgical outcomes and reduced complications for patients with lens diseases.
How similar studies have gone: While the use of optical coherence tomography in ophthalmology is established, this specific application in lens surgery is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged over 18 years old, with lens opacity or abnormal position, and other conditions meeting the surgical indications, needing lens surgery treatment, with or without anterior segment structural changes. Exclusion Criteria: * Combined with other eye diseases that seriously affect visual prognosis, serious systemic diseases and other conventional contraindications for lens surgery.
Where it's running
-
Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China Recruiting -
Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China Not yet recruiting
Study contacts
- Study coordinator: Wen Xu, PHD
- Email: xuwen2003@zju.edu.cn
- Phone: 13858185223
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
3D eye modeling to guide diagnosis and treatment of lens problems
This project will try a full 3D eye model made from multiple scans to help surgeons plan treatment for people with complex lens problems such as dislocated, traumatic, or malformed lenses.
-
Presbyopia-correcting intraocular lenses for complex cataracts with anterior segment abnormalities
This trial will test whether presbyopia-correcting intraocular lenses provide better full-range vision and reduce the need for glasses compared with standard monofocal lenses in people having cataract surgery complicated by anterior segment abnormalities.
-
Intelligent Video Laryngoscope to Help Emergency Intubations
A smart video laryngoscope with AI is tested to help doctors place tubes in critically ill adults needing emergency intubation.
-
Understanding anxiety, depression, and bipolar disorder over time in China
This study tests how anxiety, depressive, and bipolar symptoms change over three years to find patterns that help with earlier recognition and prediction in people aged 12–55.
-
Ultrasound-guided nasal bone fracture reduction
This study tests whether using ultrasound to guide nasal bone fracture reduction can improve accuracy and outcomes for people with recent nasal injuries.
-
Simplified Tranexamic Acid Regimen for Trauma with Hemorrhage
This trial tests a simplified TXA dosing approach to see if it safely helps adults with major trauma and significant bleeding.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.