Using advanced imaging to improve cataract surgery outcomes after laser eye surgery
Guiding the Treatment of Anterior Eye Diseases With Optical Coherence Tomography
This study is testing a new imaging technology to see if it can help improve cataract surgery results for people who have had laser eye surgery in the past.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 690 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Oregon Health and Science University Academic / other |
| Locations | 1 site (Portland, Oregon) |
| Trial ID | NCT00532051 on ClinicalTrials.gov |
What this trial studies
This project aims to enhance cataract surgery outcomes for patients who have previously undergone laser vision correction by utilizing high-speed Optical Coherence Tomography (OCT) technology. The study focuses on developing methods to accurately measure corneal shape and refractive power, which are critical for selecting the appropriate intraocular lens (IOL) power. By combining clinical studies with software development, the research seeks to automate the measurement of anatomical parameters essential for effective cataract surgery. The goal is to reduce the risk of significant refractive errors that can occur in patients with a history of laser refractive surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients seeking cataract surgery who have previously undergone laser vision correction procedures such as LASIK or PRK.
Not a fit: Patients with concurrent eye conditions such as retinal diseases or glaucoma, or those unable to provide informed consent, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate IOL power calculations, improving visual outcomes for patients undergoing cataract surgery after laser vision correction.
How similar studies have performed: While the use of OCT in eye imaging is established, this specific application for improving IOL power calculations in post-laser surgery patients is a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The subjects will be patients seeking cataract surgery with implantation of monofocal IOLs (including toric IOLs) but not multifocal or accommodative IOLs. * Subjects will have had post-laser vision correction (LVC) such as previous LASIK, PRK, laser sub-epithelial keratectomy (LASEK), epi-LASIK (surface laser ablation under a microkeratome-created epithelial flap) or RK. The post-LVC group will be subdivided into those who have previous hyperopic LVC and those who have previous myopic LVC. Exclusion Criteria: * Inability to give informed consent. * Inability to maintain stable fixation for OCT imaging. * Inability to commit to required visits to complete the study. * Eyes with concurrent cataract, retinal diseases, glaucoma, or other eye conditions that may limit the visual outcome after surgery.
Where this trial is running
Portland, Oregon
- Casey Eye Institute, Oregon Health & Science University — Portland, Oregon, United States (Recruiting)
Study contacts
- Principal investigator: David Huang, MD, PhD — Casey Eye Institute, Oregon Health & Science University
- Study coordinator: Humberto Martinez, COT
- Email: martinhu@ohsu.edu
- Phone: 503-494-7712
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.