Using advanced imaging during surgery for brain tumors
Intraoperative Hyperspectral Imaging for Real-time Fluorescence-guided Surgery of Low Grade Glioma
This study is testing a new imaging camera during brain surgery to see if it helps doctors better see and remove low-grade gliomas while protecting important brain areas.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | King's College London Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT05397574 on ClinicalTrials.gov |
What this trial studies
This study aims to capture images of brain tumors during surgery using a novel hyperspectral imaging camera. It will evaluate how the imaging data correlates with the actual tissue removed, enhancing the surgeon's ability to visualize tumor boundaries in real-time. The goal is to improve the precision and safety of neurosurgery, particularly for low-grade gliomas, by developing key computer-processing features that provide immediate feedback during procedures. This approach addresses the challenge of achieving complete tumor removal while preserving critical brain structures.
Who should consider this trial
Good fit: Ideal candidates include adult patients aged 18 and over with a diagnosis of glioma scheduled for elective surgery.
Not a fit: Patients under 18 years of age or those who have previously undergone brain surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this could lead to safer and more effective surgeries for patients with brain tumors, potentially improving survival rates.
How similar studies have performed: While the use of advanced imaging techniques in surgery is gaining traction, this specific approach using hyperspectral imaging for gliomas is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients aged 18 years and over * Patients with a diagnosis of a probable glioma (any grade), who are scheduled for elective surgery * Patients able to provide written informed consent Exclusion Criteria: * Patients under 18 years of age * Patients who have previously had brain surgery * Patients unable to provide written informed consent
Where this trial is running
London
- King's College NHS Foundation Trust — London, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.