Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Using advanced CT to find liver cancer spread from colorectal cancer

Official title: Role of Photon Counting CT in Detecting Liver Metastatis From Colorectal Cancer

Run by IRCCS San Raffaele · NCT06753903 · Data updated 2026-11-12

This study is testing a new type of CT scan to see if it can better find liver cancer spread in adults with colorectal cancer who haven't had a biopsy yet.

More Colorectal Cancer trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment100 (estimated)
SponsorIRCCS San Raffaele
Academic / other
Drugs / interventionsradiation
Locations1 site (Milan)
StatusRecruiting
StartedMarch 24, 2025
Main results expectedMarch 24, 2028
Study endsMarch 24, 2028
Registry record updatedJanuary 15, 2026
Trial IDNCT06753903 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years with non-biopsy-proven colorectal cancer who have undergone PCD-CT and multiparametric MRI.

Probably not a fit

Patients who are pregnant, breastfeeding, or have not undergone the required imaging protocols will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Photon Counting Computed Tomography (PCD-CT) in detecting liver metastases in patients with colorectal cancer. The study focuses on adults over 18 years who have not had a biopsy-proven diagnosis of colon or colorectal carcinoma and have undergone CT scans using PCD-CT technology. By comparing the results with multiparametric MRI, the study seeks to improve the accuracy of liver metastasis detection, which is crucial for determining treatment options and potential surgical interventions.

Why it matters

Potential benefit: If successful, this study could enhance the detection of liver metastases, leading to better treatment decisions and improved survival rates for colorectal cancer patients.

How similar studies have gone: While the use of advanced imaging techniques like PCD-CT is promising, this specific approach is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult (\>18 years)
* non- biopsy-proven colon/colorectal carcinoma
* CT performed on a PCD-CT
* MRI with multiparametric protocol and hepatospecific contrast media

Exclusion Criteria:

* pregnancy and breastfeeding
* CT exam performed on a scan different from PCD-CT
* absence of multiparametric MRI
* MRI with non hepatospecific contrast agent
* Absent informed consent signed

Where it's running

  • IRCCS San Raffaele
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.