Using advanced CT to find liver cancer spread from colorectal cancer
Role of Photon Counting CT in Detecting Liver Metastatis From Colorectal Cancer
This study is testing a new type of CT scan to see if it can better find liver cancer spread in adults with colorectal cancer who haven't had a biopsy yet.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | IRCCS San Raffaele Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Milan) |
| Trial ID | NCT06753903 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of Photon Counting Computed Tomography (PCD-CT) in detecting liver metastases in patients with colorectal cancer. The study focuses on adults over 18 years who have not had a biopsy-proven diagnosis of colon or colorectal carcinoma and have undergone CT scans using PCD-CT technology. By comparing the results with multiparametric MRI, the study seeks to improve the accuracy of liver metastasis detection, which is crucial for determining treatment options and potential surgical interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years with non-biopsy-proven colorectal cancer who have undergone PCD-CT and multiparametric MRI.
Not a fit: Patients who are pregnant, breastfeeding, or have not undergone the required imaging protocols will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the detection of liver metastases, leading to better treatment decisions and improved survival rates for colorectal cancer patients.
How similar studies have performed: While the use of advanced imaging techniques like PCD-CT is promising, this specific approach is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult (\>18 years) * non- biopsy-proven colon/colorectal carcinoma * CT performed on a PCD-CT * MRI with multiparametric protocol and hepatospecific contrast media Exclusion Criteria: * pregnancy and breastfeeding * CT exam performed on a scan different from PCD-CT * absence of multiparametric MRI * MRI with non hepatospecific contrast agent * Absent informed consent signed
Where this trial is running
Milan
- IRCCS San Raffaele — Milan, Italy (Recruiting)
Study contacts
- Study coordinator: Antonio Esposito, MD
- Email: esposito.antonio@hsr.it
- Phone: 0226436102
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.