Using a videoscope for better periodontal regeneration
Utilization of a Videoscope to Improve Clinical Outcomes of Periodontal Regeneration. A Pilot Study
This study is testing if using a videoscope during gum surgery can help people with chronic gum disease heal better than traditional methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University of Illinois at Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT05275192 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of a videoscope-assisted minimally invasive surgical approach for regenerating periodontal tissues in patients with chronic periodontitis. The study will involve 50 systemically healthy participants aged 18 to 70, who will be randomly assigned to one of three groups: videoscope-assisted surgery, traditional minimally invasive surgery, or guided tissue regeneration. The goal is to determine if enhanced visualization during surgery leads to improved clinical outcomes compared to standard methods. Participants will be monitored for their recovery and the success of the periodontal regeneration.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy individuals aged 18 to 70 with Stage III, Grade B periodontitis and specific periodontal conditions.
Not a fit: Patients with uncontrolled systemic diseases or those not referred from the Predoctoral Periodontics Student Clinics may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more predictable and effective treatments for patients suffering from chronic periodontitis.
How similar studies have performed: While minimally invasive surgical techniques are established, the use of a videoscope in this specific context is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Individual must be between the age of 18 and 70 years of age * ASA I or II systemically healthy subjects * Individuals presenting with at least 1 single or multirooted tooth with residual, isolated, interproximal bony defect with probing depths (PD) ≥ 6 mm, clinical attachment loss (CAL) ≥ 6mm, bleeding upon probing (BOP), and ≥ 2mm width of attached gingiva (WAG) * Radiographic evidence of interproximal alveolar bone loss, on existing (\< 2 years old) dental radiographs of diagnostic quality taken at the COD * Vital tooth or previous root canal therapy with no signs/symptoms of pathology * Individuals with plaque scores ≤ 20% * English speaking subjects (Individual must be willing to follow all the study requirements and participate in the study procedures in its entirety and read, understand the informed consent form) Exclusion Criteria: * Individuals not referred from the Predoctoral Periodontics Student Clinics * Uncontrolled systemic disorders such as hypertension, heart disease, bleeding disorders, metabolic bone diseases, autoimmune disorders, etc., that may influence cellular/healing status * Diabetics * Current smokers * Individual less than 18 years of age * Individuals with non-isolated, interproximal PD ≥ 4 mm extending to the facial/buccal and/or palatal/lingual tooth surfaces * Teeth with Grade 2 or 3 mobility * Teeth with metal restorations such as a porcelain fused to metal crown (due to scattering of radiographic images) * Intrabony defects on dental implants * Individual who take medications known to affect host immunity or periodontal tissues (ex. steroids, antibiotics, phenytoin, etc.) in the previous 6 months * Individuals on chronic anti-platelet/anti-coagulant therapy * Oral pathologies other than periodontal disease (ex. periapical lesions of non-periodontal origin) * Subjects who may be pregnant based on a positive pregnancy test * Non-English speaking individuals
Where this trial is running
Chicago, Illinois
- University of Illinois, Chicago, College of Dentistry, Periodontics — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Salvador Nares, DDS, PhD — University of Illinois at Chicago
- Study coordinator: Salvador Nares, DDS, PhD
- Email: snares@uic.edu
- Phone: 312-413-5787
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.