Using a synthetic membrane to improve healing after tonsil surgery

The Use of Suprathel®250 as a Novel Therapeutical Option for Mucosal Healing in Head and Neck Surgery

Phase1; Phase2 Interventional Cairo University · NCT06543823

This study is testing if a special synthetic membrane can help people heal faster and with less pain after tonsil surgery.

Quick facts

PhasePhase1; Phase2
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorCairo University Academic / other
Locations1 site (Stuttgart, Baden-Wurttemberg)
Trial IDNCT06543823 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of SupraTHEL 250, a synthetic biodegradable membrane, for mucosal reconstruction in the head and neck region following tonsillectomy. The membrane is applied to the surgical site to promote faster and less painful healing compared to traditional bare wound healing. The study aims to assess postoperative outcomes, including pain levels and healing rates, to determine if this approach enhances patient quality of life.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals experiencing recurrent episodes of tonsillar infection.

Not a fit: Patients who are children, pregnant or breastfeeding women, or those undergoing chemotherapy or radiotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce postoperative pain and complications for patients undergoing tonsillectomy.

How similar studies have performed: Previous studies have shown positive outcomes using synthetic membranes for wound healing in other contexts, suggesting potential success for this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* recurrent episodes of tonsillar infection

Exclusion Criteria:

* children
* pregnant/ breastfeeding women
* patients undergoing chemo / radiotherapy

Where this trial is running

Stuttgart, Baden-Wurttemberg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions TonsillitisPLA membraneBiodegradable membraneSyntheticTonsillectomy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.