Ondansetron lozenge versus IV to prevent shivering after tonsil removal in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children aged 4–15 undergoing tonsillectomy under general anesthesia at Tanta University will receive either an ondansetron lozenge or intravenous ondansetron and be monitored for intra- and post-operative shivering. The trial enrolls ASA I–II patients and excludes those with ondansetron allergy, sleep apnea, cardiac or respiratory disease, current upper respiratory infection, or corticosteroid use. Outcomes will include incidence and severity of shivering and related postoperative recovery measures. The comparison aims to determine whether a noninvasive lozenge route offers similar protection against shivering as the IV route.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 4 to 15 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-II.
* Children undergoing tonsillectomy under general anesthesia.

Exclusion Criteria:

* Allergy to ondansetron.
* History of sleep apnea.
* Cardiac and respiratory diseases.
* Upper respiratory tract infection.
* Taking corticosteroids.

Where it's running

• Tanta University
  Tanta, El-Gharbia, Egypt Recruiting

Study contacts

• Study coordinator: Mohammed S Elsharkawy, MD
• Email: mselsharkawy@med.tanta.edu.eg
• Phone: 00201148207870

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.