Using a spectrophotometer to predict weaning success in critically ill patients
Role of Spectrophotometer in Early Prediction of Weaning Induced Cardiac Dysfunction
This study is testing if a new method can help doctors decide the best time to take critically ill patients off mechanical ventilation to improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06674824 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the role of the plethysmography variability index (PVI) in predicting weaning-induced cardiac dysfunction in critically ill patients who are on mechanical ventilation. By utilizing a non-invasive and automated method, the study aims to determine the optimal timing for extubation based on fluid responsiveness. The study focuses on patients who meet specific criteria for extubation and have a fraction of inspired oxygen below 50%. The goal is to validate the effectiveness of PVI in improving weaning outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients who are intubated, on mechanical ventilation, and meet the criteria for extubation.
Not a fit: Patients with hemodynamic instability or those who have undergone tracheostomy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective weaning from mechanical ventilation, reducing the risk of cardiac dysfunction and improving patient recovery.
How similar studies have performed: While the use of PVI in this context is promising, it is a relatively novel approach and may not have extensive prior validation in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Intubation and mechanical ventilation 2. Fulfilling criteria for extubation 3. Fraction inspired oxygen less than 50% Exclusion Criteria: * a. Hemodynamic instability b. b. tracheostomy
Where this trial is running
Cairo
- Ain Shams University hospitals — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: amr fouad, M.D
- Email: amrfouad85@gmail.com
- Phone: 01225674370
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.