Using a smartphone app to detect absence seizures in children
A Mobile Health Application to Detect Absence Seizures Using Hyperventilation and Eye-Movement Recordings
This study is testing a smartphone app that helps find absence seizures in children by recording their breathing and movements during a special breathing exercise.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 75 (estimated) |
| Ages | 4 Years to 12 Years |
| Sex | All |
| Sponsor | Eysz, Inc. Industry-sponsored |
| Locations | 1 site (Cincinnati, Ohio) |
| Trial ID | NCT06093490 on ClinicalTrials.gov |
What this trial studies
This observational study aims to validate the Eysz mHealth App, which guides children through hyperventilation while recording video and audio data to help identify absence seizures. Children with and without a history of absence seizures will participate, allowing researchers to compare the app's performance against traditional EEG interpretations. The app captures facial expressions, eye movements, and breathing patterns during hyperventilation, a technique commonly used to provoke seizures in a controlled environment. The ultimate goal is to develop machine learning algorithms to enhance seizure detection.
Who should consider this trial
Good fit: Ideal candidates include children with a history of typical absence seizures.
Not a fit: Patients with other types of seizures or contraindications to hyperventilation may not benefit from this study.
Why it matters
Potential benefit: If successful, this app could provide a non-invasive and accessible method for detecting absence seizures in children.
How similar studies have performed: While the use of mobile applications for seizure detection is emerging, this specific approach using hyperventilation and machine learning is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * typical absence seizure during use of the Eysz Hyperventilation Recorder or Control Exclusion Criteria: * Other seizure type besides typical absence seizure during use of the Eysz Hyperventilation Recorder * subclinical seizure activity * inability to participate with study procedures * contraindications to hyperventilation including history of subarachnoid hemorrhage, sickle cell anemia, recent cerebrovascular accident or myocardial infarction, significant cardiopulmonary disease, active asthma, known aneurysm, known moyamoya disease, or pregnancy. * People who have a history of generalized tonic clonic convulsions (GTCs) provoked by hyperventilation
Where this trial is running
Cincinnati, Ohio
- Cincinnati Children's Hospital — Cincinnati, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Rachel Kuperman, MD
- Email: rkuperman@eyszlab.com
- Phone: (415) 857-1794
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.