Using a rotary cutter for vertebroplasty to treat bone metastases
Percutaneous Vertebroplasty Using Rotary Cutter for Treating Bone Metastases
This study is testing a new method using a rotary cutter during vertebroplasty to see if it can help relieve pain and prevent fractures in patients with bone metastases.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Sex | All |
| Sponsor | Jinan Military General Hospital Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT04017728 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the use of a rotary cutter in conjunction with percutaneous vertebroplasty to treat patients with bone metastases. The procedure aims to alleviate pressure within the metastases by destroying their structure, allowing for more effective cement injection that can strengthen the bone and potentially destroy tumor cells through thermal reaction. The study will assess the efficacy of this approach in relieving pain and preventing fractures in affected patients. The methodology focuses on optimizing cement diffusion patterns and doses to enhance treatment outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with imaging and pathology-proven bone metastases who experience intractable pain and neurological dysfunction.
Not a fit: Patients in poor general condition who cannot tolerate surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce pain and improve the quality of life for patients suffering from bone metastases.
How similar studies have performed: While percutaneous vertebroplasty has been widely used, the specific combination of rotary cutter and cement injection in this manner is a novel approach that has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Imaging-proven and pathology-proven metastases 2. Intractable pain with neurologic dysfunction Exclusion Criteria: 1. Poor general condition without tolerance of surgery
Where this trial is running
Jinan, Shandong
- 960 Hospital of PLA — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Min Li, M.D.
- Email: liminyingxiang@163.com
- Phone: 13953176057
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.