Using a robotic exoskeleton to help stroke survivors with arm rehabilitation

Developing and Determining Feasibility of a Novel Upper Extremity Robotic Exoskeleton to Track and Target Unwanted Joint Synergies During Repetitive Task Training in Stroke Survivors

Not applicable Interventional VA Office of Research and Development · NCT05962697

This study is testing a new robotic exoskeleton to see if it can help stroke survivors improve their arm movement and recovery during therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment7 (estimated)
Ages18 Years and up
SexAll
SponsorVA Office of Research and Development Federal
Locations1 site (Seattle, Washington)
Trial IDNCT05962697 on ClinicalTrials.gov

What this trial studies

This study aims to improve rehabilitation for stroke survivors by utilizing a newly developed robotic exoskeleton called Harmony, which facilitates bimanual 3D arm therapy. The approach involves two novel controllers designed to avoid unwanted joint synergies and assist with task performance during repetitive training. By focusing on patients in the acute and sub-acute stages of recovery, the study seeks to enhance upper extremity function and overall quality of life for Veterans. The robotic system aims to make repetitive task training more effective and less draining for both patients and clinicians.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 who have suffered a stroke within the past 1-6 months and have specific upper extremity impairment scores.

Not a fit: Patients with recurrent strokes, unstable medical conditions, or significant cognitive deficits may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance recovery outcomes and quality of life for stroke survivors by improving their upper extremity function.

How similar studies have performed: Previous studies using robotic-assisted rehabilitation have shown promise, indicating potential for success with this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* over the age of 18 years,
* have a Fugl-Meyer Upper Extremity score of 29-42 for moderately impaired (aim 1) or 0-28 for severely impaired (aim 1 and 2),
* have body dimensions within the limits of the Harmony system
* suffered a stroke within the past 1-6 months (aim 1) or 1 week (aim 2)

Exclusion Criteria:

* recurrent stroke,
* unstable cardiovascular, orthopedic, or neurological conditions,
* a history of seizure,
* significant communication deficits,
* severe upper-limb joint pain or limitations that would restrict their ability to complete the protocols,
* inadequate cognitive or language function to consent or to participate, and (7) no phone number or stable mailing address.

Where this trial is running

Seattle, Washington

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute StrokeStrokeExoskeletonupper extremityrobotrehabilitationjoint synergycontroller
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.