Using a new MRI technique to diagnose lung lesions

The Application of the New Magnetic Resonance Technique-UTE in Thoracic Lesions

Observational Fifth Affiliated Hospital, Sun Yat-Sen University · NCT05998707

This study is testing a new MRI technique to see if it can help doctors tell the difference between harmless and harmful lung lesions in patients with larger lung issues.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorFifth Affiliated Hospital, Sun Yat-Sen University Academic / other
Locations1 site (Zhuhai, Guangdong)
Trial IDNCT05998707 on ClinicalTrials.gov

What this trial studies

This study utilizes an ultrashort echo time (UTE) MRI technique to obtain quantitative characteristics of lung lesions, aiming to differentiate between benign and malignant conditions. By leveraging high-resolution zero echo time (ZTE) technology, the research seeks to enhance the diagnostic capabilities of MRI for pulmonary diseases, providing clearer images than conventional methods. The study focuses on patients with lung lesions that are at least 6mm in size and evaluates the feasibility of this advanced imaging approach in clinical settings.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with lung lesions measuring 6mm or more.

Not a fit: Patients with metal implants in the chest, MRI contrast agent allergies, or those who are pregnant will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of lung lesion diagnoses, leading to better treatment decisions for patients.

How similar studies have performed: Previous studies have shown promising results using similar MRI techniques for evaluating lung conditions, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥18 years old;
2. There are lung lesions, and the solid component is ≥6mm;
3. Chest CT plain scan or /+ enhanced examination within 4 weeks.

Exclusion Criteria:

1. There are metal implants in the corresponding parts of the chest;
2. MRI contrast agent allergy;
3. Claustrophobia;
4. Pregnant women;
5. High fever;
6. Respiratory failure;
7. Lung lesion biopsy within 4 weeks prior to examination.

Where this trial is running

Zhuhai, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung DiseasesLung mass, UTE, ZTE, nodule, MRI
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.