Using a nerve block for pain relief after laparoscopic adrenal surgery
Effect of Thoracic Paravertebral Block on Analgesia and the Quality of Recovery Following Daytime Laparoscopic Partial Adrenalectomy
This study is testing whether a special nerve block can help people feel less pain and recover better after laparoscopic adrenal surgery compared to standard pain management.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Shanxi Bethune Hospital Academic / other |
| Locations | 1 site (Taiyuan, Shanxi) |
| Trial ID | NCT06566521 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of thoracic paravertebral block (TPVB) for postoperative analgesia in patients undergoing daytime laparoscopic partial adrenalectomy. It is a single-center, double-blind, randomized-controlled trial involving 70 participants, who are divided into two groups: one receiving the TPVB and the other receiving standard care without nerve blockade. The study aims to assess the quality of recovery and pain management following surgery, with a focus on minimizing hospital stays and optimizing recovery outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 70 with a BMI between 18.5 and 30, classified as ASA grade I to II, and diagnosed with a unilateral non-functional adrenal adenoma larger than 20mm.
Not a fit: Patients with peripheral nervous system diseases, spinal deformities, coagulation abnormalities, or those with a history of severe postoperative nausea and vomiting may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and recovery quality for patients undergoing laparoscopic adrenal surgery.
How similar studies have performed: Previous studies have indicated that similar approaches using regional anesthesia techniques have been successful in improving postoperative outcomes, suggesting this method may also yield positive results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 to70 years * Body Mass Index (BMI) 18.5 to 30 kg/m² * American Society of Anesthesiologists (ASA) grade I to II classification * unilateral non-functional adrenal adenoma with a tumor diameter greater than 20mm Exclusion Criteria: * Patients with peripheral nervous system disease * Patients with spinal deformity or surgery * Patients with puncture site infection or coagulation abnormalities * Patients with history of postoperative nausea and vomiting or allergy to local anesthetics * Patients with unstable mental illness or refusal to participate
Where this trial is running
Taiyuan, Shanxi
- Shanxi Bethune Hospital — Taiyuan, Shanxi, China (Recruiting)
Study contacts
- Principal investigator: Jian-Wen Zhang, MD — Shanxi Bethune Hospital
- Study coordinator: Jian-Wen Zhang, MD
- Email: zjw030001@126.com
- Phone: +86 13994299284
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.